UACA anticorps
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- Antigène Voir toutes UACA Anticorps
- UACA
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp UACA est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Purification
- Protein G affinity chromatography
- Immunogène
- Nuclei of myeloid leukemia biopsy cells were used as the immunogen for the UACA antibody.
- Clone
- AE-5
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product UACA Anticorps primaire
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- Indications d'application
- Optimal dilution of the UACA antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Western blot: 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store the UACA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Antigène
- UACA
- Autre désignation
- UACA (UACA Produits)
- Synonymes
- anticorps NUCLING, anticorps 2700059D02Rik, anticorps nucling, anticorps RGD1560011, anticorps uveal autoantigen with coiled-coil domains and ankyrin repeats, anticorps UACA, anticorps Uaca
- Sujet
- UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
- Pathways
- Positive Regulation of Endopeptidase Activity
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