STRADB anticorps (Internal Region)

N° du produit ABIN3024145

Détail du produit anti-STRADB anticorps

Antigène: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STRADB est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A affinity chromatography

Immunogène: A recombinant protein fragment from the interior region of human Als2Cr2 was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: Provided assay concentrations are suggestions only, Als2Cr2 antibody titration may be required for optimal results. This antibody will detect the 418 (ILPIP alpha) and 280 (ILPIP beta) amino acid isoforms.\. Western blot: 5-10 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Als2Cr2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur STRADB

Antigène: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Autre désignation: Als2Cr2 (STRADB Produits)

Synonymes: anticorps Als2cr2, anticorps RGD1559449, anticorps als2cr2, anticorps MGC82468, anticorps STRADB, anticorps ALS2CR2, anticorps AA792893, anticorps B830008M19, anticorps D1Ucla2, anticorps ILPIP, anticorps ILPIPA, anticorps PRO1038, anticorps Papk, anticorps Syradb, anticorps CALS-21, anticorps PAPK, anticorps STE20-related kinase adaptor beta, anticorps STE20-related kinase adaptor beta L homeolog, anticorps Stradb, anticorps STRADB, anticorps stradb.L

Sujet: Als2Cr2, also called STE20-related kinase adapter protein beta (STRAD beta) and ILPIP, is a serine/threonine protein kinase encoded by the STRADB gene, discovered as an XIAP interacting protein. It is a mediator of the XIAP/TAK1 activation of the JNK1 pathway, an apoptosis inhibition mechanism independent of XIAP inhibition of caspases. Alone, it only moderately activates JNKs, but its interaction with XIAP/TAK1 induces a much stronger activation of JNK1, protecting against Caspase 1- or Fas-induced apoptosis.

ID gène: 55437

Pathways: AMPK Signaling