YBX1 anticorps (Middle Region)
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- Antigène Voir toutes YBX1 Anticorps
- YBX1 (Y Box Binding Protein 1 (YBX1))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp YBX1 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Antigen affinity
- Immunogène
- An amino acid sequence from the middle region of human YBX1 (KYAADRNHYRRYPRRR) was used as the immunogen for this YB1 antibody (100% homologous in human, mouse and rat).
- Isotype
- IgG
- Top Product
- Discover our top product YBX1 Anticorps primaire
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- Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the YB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the YB1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- YBX1 (Y Box Binding Protein 1 (YBX1))
- Autre désignation
- YB1 (YBX1 Produits)
- Synonymes
- anticorps BP-8, anticorps CSDA2, anticorps CSDB, anticorps DBPB, anticorps MDR-NF1, anticorps NSEP-1, anticorps NSEP1, anticorps YB-1, anticorps YB1, anticorps Byb1, anticorps Cbfa, anticorps Dbpb, anticorps Ef1a, anticorps Msy1, anticorps Nsep1, anticorps Yb1, anticorps bp-8, anticorps csda2, anticorps csdb, anticorps dbpb, anticorps frgy1, anticorps mdr-nf1, anticorps nsep-1, anticorps nsep1, anticorps yb1, anticorps 1700102N10Rik, anticorps C79409, anticorps EF1A, anticorps MSY1, anticorps dbpB, anticorps mYB-1a, anticorps nuclease sensitive element binding protein 1, anticorps Y-box binding protein 1, anticorps Y box binding protein 1, anticorps Y-box binding protein 1 S homeolog, anticorps nuclease-sensitive element-binding protein 1, anticorps Y box protein 1, anticorps nsep1, anticorps YBX1, anticorps Ybx1, anticorps ybx1.S, anticorps LOC479011
- Sujet
- Y box binding protein 1, commonly referred to as YBX1 or just YB1 by researchers, is a human protein. YBX1 binding has an absolute requirement for the CCAAT box and relative specificity for the Y box. It has a molecular mass of 35,414D and contains 18 % basic residues and putative nuclear localization signals. The protein is highly expressed in mouse erythroid myeloid lymphoid clone-1 (EML), a hematopoietic precursor cell line, but is downregulated in myeloid progenitors and in Gmcsf-treated EML cells during myeloid differentiation. YBX1 is expressed at high levels in myeloid leukemic cells at different developmental stages. Knockdown of the protein in a human leukemic cell line inhibited proliferation ability, induced apoptosis, and induced megakaryocytic differentiation in response to arsenic trioxide treatment. YBX1 is downregulated during myeloid differentiation and aberrant expression in leukemic cells may contribute to leukemia development by blocking differentiation.
- UniProt
- P67809
- Pathways
- Regulation of Muscle Cell Differentiation
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