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APLP1 anticorps (N-Term)

APLP1 Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3029932
  • Antigène Voir toutes APLP1 Anticorps
    APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
    Épitope
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 34
    • 32
    • 16
    • 6
    • 5
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 45
    • 2
    Lapin
    Clonalité
    • 46
    • 1
    Polyclonal
    Conjugué
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp APLP1 est non-conjugé
    Application
    • 33
    • 13
    • 13
    • 8
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity
    Immunogène
    An amino acid sequence from the N-terminus of human Amyloid-precursor-like protein 1 (ELQIARVEQATQAIPMERWC) was used as the immunogen for this APLP1 antibody.
    Isotype
    IgG
    Top Product
    Discover our top product APLP1 Anticorps primaire
  • Indications d'application
    The stated application concentrations are suggested starting amounts. Titration of the APLP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    After reconstitution, the APLP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène
    APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
    Autre désignation
    APLP1 (APLP1 Produits)
    Synonymes
    anticorps aplp, anticorps MGC115336, anticorps APLP, anticorps Aplp1_retired, anticorps RGD1561211, anticorps amyloid beta precursor like protein 1, anticorps amyloid beta precursor like protein 1 L homeolog, anticorps amyloid beta (A4) precursor-like protein 1, anticorps APLP1, anticorps aplp1.L, anticorps aplp1, anticorps Aplp1
    Sujet
    Amyloid-precursor-like protein 1 is a membrane-associated glycoprotein, whose gene is homologous to the APP gene, which has been shown to be involved in the pathogenesis of Alzheimers disease. APLP1 is predominantly expressed in brain, particularly in the cerebral cortex postsynaptic density. The human gene has been mapped to chromosomal region 19q13.1. The gene is 11.8 kb long and contains 17 exons. APLP1 has been considered a candidate gene for CNF. All exon regions of the gene were amplified by the polymerase chain reaction and sequenced from DNA of CNF patients. No differences were observed between CNF patients and controls, suggesting that mutations in APLP1 are not involved in the etiology of CNF.
    UniProt
    P51693
    Pathways
    cAMP Metabolic Process
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