ABCG4
Reactivité: Humain
WB, ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
The stated application concentrations are suggested starting amounts. Titration of the ABCG4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
-20 °C
Stockage commentaire
After reconstitution, the ABCG4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Antigène
ABCG4
(ATP-Binding Cassette, Sub-Family G (WHITE), Member 4 (ABCG4))
anticorps WHITE2, anticorps 6430517O04Rik, anticorps zgc:171697, anticorps ATP binding cassette subfamily G member 4, anticorps ATP-binding cassette sub-family G member 4, anticorps ATP-binding cassette, sub-family G (WHITE), member 4a, anticorps ATP-binding cassette, sub-family G (WHITE), member 4b, anticorps ABCG4, anticorps CpipJ_CPIJ007191, anticorps CpipJ_CPIJ012365, anticorps CpipJ_CPIJ012372, anticorps CpipJ_CPIJ014443, anticorps CpipJ_CPIJ019125, anticorps CpipJ_CPIJ020198, anticorps PAAG_06842, anticorps Abcg4, anticorps LOC550918, anticorps abcg4a, anticorps abcg4b
Sujet
ATP-Binding Cassette, Subfamily G, Member 4 is a protein that in humans is encoded by the ABCG4 gene. The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. This protein is a member of the White subfamily and is expressed predominantly in liver tissue. By genomic sequence analysis, Engel et al.(2001) mapped the gene to chromosome 11q23.3. Engel et al.(2001) demonstrated 5-fold induction of ABCG4 following treatment of normal monocyte-derived macrophages with the LXR and RXR agonists 9-cis retinoic acid and 22R hydroxycholesterol. Removal of cholesterol from macrophages by cyclodextrin decreased ABCG4 message levels.