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CAMKK2 anticorps (Middle Region)

CAMKK2 Reactivité: Humain, Souris, Rat WB, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3030259
  • Antigène Voir toutes CAMKK2 Anticorps
    CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
    Épitope
    • 18
    • 16
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 63
    • 41
    • 24
    • 18
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 70
    • 7
    Lapin
    Clonalité
    • 72
    • 5
    Polyclonal
    Conjugué
    • 38
    • 7
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CAMKK2 est non-conjugé
    Application
    • 72
    • 35
    • 21
    • 14
    • 10
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Purification
    Antigen affinity
    Immunogène
    An amino acid sequence from the middle region of CaMKK2 (KLAYNENDNTYYAMK) was used as the immunogen for this CaMKK2 antibody (100% homologous in human, mouse and rat).
    Isotype
    IgG
    Top Product
    Discover our top product CAMKK2 Anticorps primaire
  • Indications d'application
    The stated application concentrations are suggested starting amounts. Titration of the CaMKK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    After reconstitution, the CaMKK2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène
    CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
    Autre désignation
    CaMKK2 (CAMKK2 Produits)
    Synonymes
    anticorps CAMKK, anticorps CAMKKB, anticorps 6330570N16Rik, anticorps AW061083, anticorps mKIAA0787, anticorps camk2b, anticorps fj90d04, anticorps wu:fj90d04, anticorps si:dkey-174n20.2, anticorps CAMKK2, anticorps calcium/calmodulin dependent protein kinase kinase 2, anticorps calcium/calmodulin-dependent protein kinase kinase 2, beta, anticorps calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1, anticorps calcium/calmodulin dependent protein kinase II beta, anticorps calcium/calmodulin-dependent protein kinase kinase 2, anticorps CAMKK2, anticorps Camkk2, anticorps camk2b1, anticorps CAMK2B, anticorps camkk2
    Sujet
    Calcium/calmodulin-dependent protein kinase kinase 2, is an enzyme that in humans is encoded by the CaMKK2 gene. The product of this gene belongs to the serine/threonine-specific protein kinase family, and to the Ca++/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent(CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. CaMKK2 regulates production of the appetite stimulating hormone neuropeptide Y and functions as an AMPK kinase in the hypothalamus. It also has an important role in the development of hyperalgesia and tolerance to opioid analgesic drugs, through reduction in downstream signalling pathways and mu opioid receptor downregulation. Inhibition of CaMKK2 in mice reduces appetite and promotes weight loss.
    UniProt
    Q96RR4
    Pathways
    AMPK Signaling
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