CXCL1 anticorps (C-Term)

N° du produit ABIN3030502

Détail du produit anti-CXCL1 anticorps

Antigène: CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCL1 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human GROA (KMLNSDKSN) was used as the immunogen for this GRO alpha antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the GRO alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the GRO alpha antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur CXCL1

Antigène: CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))

Autre désignation: GRO alpha (CXCL1 Produits)

Synonymes: anticorps FSP, anticorps GRO1, anticorps GROa, anticorps MGSA, anticorps MGSA-a, anticorps NAP-3, anticorps SCYB1, anticorps CINC-1, anticorps Gro1, anticorps CXCL1, anticorps Sdf1, anticorps Fsp, anticorps KC, anticorps Mgsa, anticorps N51, anticorps Scyb1, anticorps gro, anticorps GRO, anticorps Gro, anticorps C-X-C motif chemokine ligand 1, anticorps chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha), anticorps C-X-C motif chemokine ligand 12, anticorps chemokine (C-X-C motif) ligand 1, anticorps CXCL1, anticorps Cxcl1, anticorps Cxcl12, anticorps GRO1

Sujet: CXCL1 (Chemokine, CXC motif, Ligand 1), also called GRO1, SCYB1, GROA or MGSA, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO alpha, KC, Neutrophil-activating protein 3(NAP-3) and melanoma growth stimulating activity, alpha (MSGA-alpha). In humans, this protein is encoded by the CXCL1 gene. It is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. It is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1/GROA plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation,wound healing, and tumorigenesis. Signaling through CXCR2, CXCL1/GROA inhibited oligodendrocyte precursor migration. The migrational arrest was rapid, reversible, and concentration dependent, and it reflected enhanced cell/substrate interactions.

UniProt: P09341

Pathways: Autophagy