CXCR2 anticorps

N° du produit ABIN3030509

Détail du produit anti-CXCR2 anticorps

Antigène: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR2 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Amino acids CYEDMGNNTANWRMLLR were used as the immunogen for this CXCR2 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the CXCR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CXCR2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur CXCR2

Antigène: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Autre désignation: CXCR2 (CXCR2 Produits)

Synonymes: anticorps CD182, anticorps CDw128b, anticorps CMKAR2, anticorps IL8R2, anticorps IL8RA, anticorps IL8RB, anticorps CXC-R2, anticorps CXCR-2, anticorps CD128, anticorps CDw128, anticorps Cmkar2, anticorps Gpcr16, anticorps IL-8Rh, anticorps IL-8rb, anticorps Il8rb, anticorps mIL-8RH, anticorps C-X-C motif chemokine receptor 2, anticorps chemokine (C-X-C motif) receptor 2, anticorps Cxcr2, anticorps CXCR2

Sujet: CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family(subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.

UniProt: P25025

Pathways: cAMP Metabolic Process