CXCR6 anticorps (C-Term)

N° du produit ABIN3030518

Détail du produit anti-CXCR6 anticorps

Antigène: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human Chemokine CXC Motif Receptor 6 (EDNSKTFSASHNVEATSMFQL) was used as the immunogen for this CXCR6 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the CXCR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CXCR6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur CXCR6

Antigène: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Autre désignation: CXCR6 (CXCR6 Produits)

Synonymes: anticorps BONZO, anticorps CD186, anticorps STRL33, anticorps TYMSTR, anticorps BB217514, anticorps C-X-C motif chemokine receptor 6, anticorps chemokine (C-X-C motif) receptor 6 L homeolog, anticorps chemokine (C-X-C motif) receptor 6, anticorps CXCR6, anticorps cxcr6.L, anticorps Cxcr6

Sujet: Chemokine CXC Motif Receptor 6, also known as STRL33 and Bonzo, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al.(1997) mapped the single-copy gene to chromosome 3. Matloubian et al.(2000) found that human and mouse cells expressing the protein showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 most likely function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al.(2001) concluded that the proteinb may be important in the trafficking of effector T cells mediating type-1 inflammation.

UniProt: O00574