COL4A1 anticorps (AA 1445-1669)

N° du produit ABIN3030553

Détail du produit anti-COL4A1 anticorps

Antigène: COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))

Épitope: AA 1445-1669

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL4A1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 1445-1669) was used as the immunogen for this Collagen IV antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Collagen IV antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Collagen IV antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur COL4A1

Antigène: COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))

Autre désignation: Collagen IV / COL4A1 (COL4A1 Produits)

Synonymes: anticorps col4a1, anticorps wu:fc02g11, anticorps HANAC, anticorps ICH, anticorps POREN1, anticorps arresten, anticorps Bru, anticorps Col4a-1, anticorps Del(8)44H, anticorps Raw, anticorps Svc, anticorps collagen, type IV, alpha 5 (Alport syndrome), anticorps collagen type IV alpha 1 chain, anticorps collagen, type IV, alpha 1, anticorps col4a5, anticorps COL4A1, anticorps Col4a1

Sujet: COL4A1, also known as ICH or Collagen alpha-1(IV), is a protein that in humans is encoded by the COL4A1 gene. It is mapped to 13q34. This gene encodes the major type IV alpha collagen chain of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. COL4A1 binds to alpha-1/beta-1 integrin and inhibits migration, proliferation, and tube formation by endothelial cells. It is also a potential therapeutic candidate for targeting tumor angiogenesis.

ID gène: 1282

Pathways: Skeletal Muscle Fiber Development, Growth Factor Binding