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Dopamine Receptor d1 anticorps (AA 221-242)

DRD1 Reactivité: Humain, Rat, Souris WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3030766
  • Antigène Voir toutes Dopamine Receptor d1 (DRD1) Anticorps
    Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))
    Épitope
    • 16
    • 16
    • 14
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-242
    Reactivité
    • 79
    • 66
    • 43
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 85
    • 5
    • 1
    Lapin
    Clonalité
    • 77
    • 13
    Polyclonal
    Conjugué
    • 36
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Dopamine Receptor d1 est non-conjugé
    Application
    • 68
    • 32
    • 27
    • 26
    • 26
    • 26
    • 17
    • 17
    • 15
    • 9
    • 8
    • 8
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity
    Immunogène
    Amino acids 221-242 (AQKQIRRIAALERAAVHAKNCQ-human) were used as the immunogen for this DRD1 antibody.
    Isotype
    IgG
    Top Product
    Discover our top product DRD1 Anticorps primaire
  • Indications d'application
    Titration of the Dopamine Receptor D1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    The DRD1 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaws.
  • Antigène
    Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))
    Autre désignation
    DRD1 Dopamine Receptor D1 (DRD1 Produits)
    Synonymes
    anticorps DRD1, anticorps Dop1, anticorps D1A, anticorps DADR, anticorps DRD1A, anticorps drd1, anticorps C030036C15Rik, anticorps Drd-1, anticorps Drd1, anticorps Gpcr15, anticorps D1a, anticorps Drd1a, anticorps dopamine receptor D1, anticorps dopamine receptor, D1, anticorps dopamine receptor D1b, anticorps DRD1, anticorps Dop1, anticorps drd1b, anticorps Drd1
    Sujet
    Dopamine receptor D1 is the most highly expressed DA receptor subtype among the DA receptor family. Receptors for dopamine have been classified into two functional types, D1 and D2. They belong to the family of receptors acting through G (or guanine nucleotide-binding) proteins. D2Rs inhibit adenylyl cyclase, but D1Rs stimulate adenylyl cyclase and activate cyclic AMP-dependent protein kinases. DRD1/2 are targets of drug therapy in many psychomotor disorders, including Parkinson's disease and schizophrenia, and may also have a role in drug addiction and alcoholism. D1Rs regulate neuron growth and differentiation, influence behaviour and modify DRD2-mediated events. And the presence of a DRD1 gene restriction fragment length polymorphism will be helpful for future disease linkage studies. This protein also regulates the neurochemical architecture of the striatum and is critical for the normal expression of motor activity.
    UniProt
    P21728
    Pathways
    cAMP Metabolic Process, Inositol Metabolic Process, Protein targeting to Nucleus, Feeding Behaviour, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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