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E2F2 anticorps (C-Term)

E2F2 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3030789
  • Antigène Voir toutes E2F2 Anticorps
    E2F2 (E2F Transcription Factor 2 (E2F2))
    Épitope
    • 9
    • 7
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 61
    • 39
    • 17
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 56
    • 5
    Lapin
    Clonalité
    • 50
    • 11
    Polyclonal
    Conjugué
    • 32
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp E2F2 est non-conjugé
    Application
    • 44
    • 24
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Antigen affinity
    Immunogène
    An amino acid sequence from the C-terminus of human E2F transcription factor 2 (ISDLFDSYDLGDLLIN) was used as the immunogen for this E2F2 antibody (100% mouse homology).
    Isotype
    IgG
    Top Product
    Discover our top product E2F2 Anticorps primaire
  • Indications d'application
    The stated application concentrations are suggested starting amounts. Titration of the E2F2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    After reconstitution, the E2F2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène
    E2F2 (E2F Transcription Factor 2 (E2F2))
    Autre désignation
    E2F2 (E2F2 Produits)
    Synonymes
    anticorps E2F-2, anticorps CG1071, anticorps Dmel\\CG1071, anticorps E2F, anticorps E2F2, anticorps dE2F-2, anticorps dE2F2, anticorps dE2f2, anticorps de2f2, anticorps e2f2, anticorps 9230110J10, anticorps E130207A07, anticorps fb40b03, anticorps wu:fb40b03, anticorps E2F transcription factor 2, anticorps si:ch211-160f23.5, anticorps E2F2, anticorps E2f2, anticorps si:ch211-160f23.5
    Sujet
    E2F transcription factor 2, also called E2F-2, is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The gene is mapped to 1p36 by fluorescence in situ hybridization. Electrophoretic mobility shift assays revealed the specific binding of E2F2 to ECE1b promoter sequences containing either allele of the C-338A polymorphism, with the -338A allele being associated with an increased affinity to E2F2 compared with -338C. The ability of Myc to induce S phase was impaired in the absence of either E2f2 or E2f3 but not E2f1 or E2f4. In contrast, the ability of Myc to induce apoptosis was markedly reduced in cells deleted for E2f1 but not E2f2 or E2f3.
    UniProt
    Q14209
    Pathways
    Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication
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