GATA2 anticorps (N-Term)

N° du produit ABIN3031027

Détail du produit anti-GATA2 anticorps

Antigène: GATA2 (GATA Binding Protein 2 (GATA2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GATA2 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the N-terminus of human GATA2 (DVFFNHLDSQGNPYY) was used as the immunogen for this GATA2 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the GATA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the GATA2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur GATA2

Antigène: GATA2 (GATA Binding Protein 2 (GATA2))

Autre désignation: GATA2 (GATA2 Produits)

Synonymes: anticorps DCML, anticorps MONOMAC, anticorps NFE1B, anticorps Gata-2, anticorps xgata-2, anticorps xgata2, anticorps GATA-2, anticorps NF-E1b, anticorps GATA2, anticorps Gata2, anticorps gata2, anticorps zg2, anticorps zgc:91840, anticorps GATA binding protein 2, anticorps GATA binding protein 2 L homeolog, anticorps amidase, anticorps glutamyl/aspartyl-tRNA(Gln/Asp) amidotransferasesubunit A, anticorps hypothetical protein, anticorps glutamyl-tRNA(Gln) amidotransferase, subunit GatA (Glu-ADT subunit A), anticorps GATA2 transcription factor, anticorps putative gata binding factor, anticorps GATA binding protein 2a, anticorps GATA binding protein 2b, anticorps GATA2, anticorps Gata2, anticorps gata2.L, anticorps RR_RS20245, anticorps gatA2, anticorps Smp_018590, anticorps gata2a, anticorps gata2b

Sujet: The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells. Ciciotte et al.(1997) mapped the mouse GATA2 gene to chromosome 6 by study of DNA from an interspecific backcross panel. They pointed out that the human gene had been mapped to chromosome 3 by Dorfman et al.(1992) using DNA from a panel of 12 rodent/human hybrids containing various human chromosomes and applying Southern blot analysis. By exon trapping using a PAC contig spanning a breakpoint region associated with myeloid leukemia, Wieser et al.(2000) mapped the GATA2 gene to chromosome 3q21. GATA2 is transcribed from telomere to centromere. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells.

UniProt: P23769

Pathways: Stem Cell Maintenance