GCLC anticorps (N-Term)
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- Antigène Voir toutes GCLC Anticorps
- GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GCLC est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity
- Immunogène
- An amino acid sequence from the N-terminus of human GCLC (GSPLSWEETKRHADHVRR) was used as the immunogen for this GCLC antibody.
- Isotype
- IgG
- Top Product
- Discover our top product GCLC Anticorps primaire
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- Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the GCLC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the GCLC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
- Autre désignation
- GCLC (GCLC Produits)
- Synonymes
- anticorps GCLC, anticorps gclc, anticorps MGC146287, anticorps 2259, anticorps CG2259, anticorps DmGCLC, anticorps DmGCS, anticorps DmGCSh, anticorps Dmel\\CG2259, anticorps GCL, anticorps GCLc, anticorps GCSh, anticorps Gcs, anticorps Gcsh, anticorps DDBDRAFT_0186120, anticorps DDBDRAFT_0231403, anticorps DDB_0186120, anticorps DDB_0231403, anticorps GCS, anticorps GLCL, anticorps GLCLC, anticorps D9Wsu168e, anticorps GLCL-H, anticorps Ggcs-hs, anticorps Glclc, anticorps cb1049, anticorps fe36e11, anticorps wu:fe36e11, anticorps glutamate-cysteine ligase catalytic subunit, anticorps glutamate-cysteine ligase, catalytic subunit, anticorps Glutamate-cysteine ligase catalytic subunit, anticorps gamma glutamylcysteine synthetase, anticorps glutamate-cysteine ligase, catalytic subunit L homeolog, anticorps glutamate-cysteine ligase, catalytic subunit S homeolog, anticorps gamma-glutamylcysteine synthetase, anticorps GCLC, anticorps gclc, anticorps Gclc, anticorps LbGCS, anticorps gcsA, anticorps gclc.L, anticorps gclc.S, anticorps GSH1
- Sujet
- Glutamate--cysteine ligase catalytic subunit, is an enzyme that in humans is encoded by the GCLC gene. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. The gene encoding the catalytic subunit encodes a protein of 367 amino acids with a calculated molecular weight of 72.773 kDa and maps to chromosome 6p12.1. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia.
- UniProt
- P48506
- Pathways
- Cell RedoxHomeostasis
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