IGFBP3 anticorps (Middle Region)

N° du produit ABIN3031353

Détail du produit anti-IGFBP3 anticorps

Antigène: IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGFBP3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: An amino acid sequence from the middle region of human IGFBP3 (IKKGHAKDSQRYKVDYE) was used as the immunogen for this IGFBP3 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the IGFBP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the IGFBP3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur IGFBP3

Antigène: IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))

Autre désignation: IGFBP3 (IGFBP3 Produits)

Synonymes: anticorps BP-53, anticorps IBP3, anticorps AI649005, anticorps IGFBP-3, anticorps IGgfbp3, anticorps IGF-BP3, anticorps zgc:91788, anticorps IGFBP3, anticorps igfbp3, anticorps insulin like growth factor binding protein 3, anticorps insulin-like growth factor binding protein 3, anticorps IGFBP3, anticorps Igfbp3, anticorps igfbp3, anticorps IGFBP-3, anticorps LOC100305016

Sujet: Insulin-like growth fator-binding protein 3, is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. IGFBP3 is located on chromosome 7. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit(IGFALS) and either insulin-like growth factor(IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: P17936

Pathways: Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding