KLF5 anticorps (Middle Region)

N° du produit ABIN3031574

Détail du produit anti-KLF5 anticorps

Antigène: KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF5 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the middle region of human Kruppel-like factor 5 (HKKYRRDSASVVDQFFTD) was used as the immunogen for this KLF5 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the KLF5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the KLF5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur KLF5

Antigène: KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))

Autre désignation: KLF5 (KLF5 Produits)

Synonymes: anticorps KLF5, anticorps klf5, anticorps MGC115081, anticorps BTEB2, anticorps Bteb2, anticorps IKLF, anticorps bteb2, anticorps 4930520J07Rik, anticorps CKLF, anticorps Kruppel like factor 5, anticorps Kruppel-like factor 5 (intestinal) S homeolog, anticorps Kruppel-like factor 5, anticorps KLF5, anticorps klf5.S, anticorps Klf5

Sujet: Kruppel-like factor 5 is a protein that in humans is encoded by the KLF5 gene. It is also known as BTEB2. This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Suske et al.(2005) stated that the human gene maps to chromosome 13q21.33, and the mouse gene to chromosome 14E2.1. Sogawa et al.(1993) isolated a cDNA encoding KLF5. The predicted protein contains 3 consecutive zinc finger motifs near the C terminus. The zinc finger domains were 59 % and 64 % identical to those of Sp1 (189906) and BTEB1, respectively. Both KLF5 and Sp1 have a short basic region preceding the zinc finger motifs that may play an auxiliary role in DNA binding. The N-terminal region of KLF5 is proline rich. Recombinant KLF5 protein and Sp1 showed very similar DNA-binding specificity in vitro. When expressed in mammalian cells, KLF5 activated the transcription of a reporter gene fused to a GC box-containing promoter. Sogawa et al.(1993) also identified the rat homolog.

UniProt: Q13887