OPTN anticorps (AA 241-577)

N° du produit ABIN3032098

Détail du produit anti-OPTN anticorps

Antigène: OPTN (Optineurin (OPTN))

Épitope: AA 241-577

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OPTN est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 241-577) was used as the immunogen for this Optineurin antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Optineurin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Optineurin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur OPTN

Antigène: OPTN (Optineurin (OPTN))

Autre désignation: Optineurin (OPTN Produits)

Synonymes: anticorps nrp, anticorps fip2, anticorps hip7, anticorps hypl, anticorps glc1e, anticorps tfiiia-intp, anticorps ALS12, anticorps FIP2, anticorps GLC1E, anticorps HIP7, anticorps HYPL, anticorps NRP, anticorps TFIIIA-INTP, anticorps Fip2, anticorps 4930441O07Rik, anticorps fj52f04, anticorps si:ch211-240l19.3, anticorps wu:fj52f04, anticorps zgc:66386, anticorps zgc:77868, anticorps optineurin, anticorps optineurin L homeolog, anticorps OPTN, anticorps optn, anticorps Optn, anticorps optn.L

Sujet: OPTN is also known as NRP, FIP2 or HYPL. This gene encodes the coiled-coil containing protein Optineurin which may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize < a href=../search_result.php?search_txt=TNFa>tumor necrosis factor-alpha or < a href=../search_result.php?search_txt=fas ligand>Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. It may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the < a href=../search_result.php?search_txt=rab8>RAB8, < a href=../search_result.php?search_txt=huntingtin>Huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

ID gène: 10133

Pathways: M Phase