PGK1 anticorps (Middle Region)

N° du produit ABIN3032222

Détail du produit anti-PGK1 anticorps

Antigène: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGK1 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the middle region of human Phosphoglycerate Kinase 1 (FGTAHRAHSSMVGVN) was used as the immunogen for this PGK1 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the PGK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL, IHC-P: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the PGK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur PGK1

Antigène: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Autre désignation: PGK1 (PGK1 Produits)

Synonymes: anticorps MIG10, anticorps PGKA, anticorps Pgk-1, anticorps Pgk, anticorps PGK, anticorps wu:fd59b07, anticorps wu:fj36g06, anticorps zgc:56252, anticorps zgc:77899, anticorps PGK1, anticorps phosphoglycerate kinase 1, anticorps pgk2, anticorps pgka, anticorps phosphoglycerate kinase 1, anticorps phosphoglycerate kinase 1 L homeolog, anticorps PGK1, anticorps Pgk1, anticorps pgk1, anticorps LOC100348124, anticorps pgk1.L

Sujet: Phosphoglycerate Kinase 1, also known as PGKA, is an enzyme that in humans is encoded by the PGK1 gene. Willard et al.(1985) used a cDNA for human PGK to map the functional PGK1 gene to Xq13. Disulfide bonds in secreted proteins are considered to be inert because of the oxidizing nature of the extracellular milieu. An exception to this rule is a reductase secreted by tumor cells that reduces disulfide bonds in the serine proteinase plasmin. Lay et al.(2000) showed that the plasmin reductase isolated from conditioned medium of fibrosarcoma cells is the glycolytic enzyme phosphoglycerate kinase. Recombinant phosphoglycerate kinase had the same specific activity as the fibrosarcoma-derived protein. Plasma of mice bearing fibrosarcoma tumors contained several-fold more phosphoglycerate kinase, as compared with mice without tumors.

UniProt: P00558

Pathways: Cellular Glucan Metabolic Process