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Prolactin Receptor anticorps (C-Term)

PRLR Reactivité: Humain, Rat, Souris WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3032320
  • Antigène Voir toutes Prolactin Receptor (PRLR) Anticorps
    Prolactin Receptor (PRLR)
    Épitope
    • 15
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 73
    • 31
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 46
    • 31
    • 2
    • 2
    Lapin
    Clonalité
    • 46
    • 34
    • 1
    Polyclonal
    Conjugué
    • 45
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Prolactin Receptor est non-conjugé
    Application
    • 53
    • 22
    • 21
    • 19
    • 19
    • 17
    • 13
    • 13
    • 10
    • 9
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity
    Immunogène
    An amino acid sequence from the C-terminus of mouse Prolactin Receptor (QLGRLDYLDPTCFMH) was used as the immunogen for this Prolactin Receptor antibody (100% rat homology).
    Isotype
    IgG
    Top Product
    Discover our top product PRLR Anticorps primaire
  • Indications d'application
    The stated application concentrations are suggested starting amounts. Titration of the Prolactin Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    After reconstitution, the Prolactin Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène
    Prolactin Receptor (PRLR)
    Autre désignation
    Prolactin Receptor (PRLR Produits)
    Synonymes
    anticorps hPRLrI, anticorps PRL-R, anticorps prlr, anticorps PRLRb, anticorps PRLR, anticorps tprlr, anticorps DKFZp469D061, anticorps RATPRLR, anticorps AI987712, anticorps Pr-1, anticorps Pr-3, anticorps Prlr-rs1, anticorps wu:fj65c07, anticorps prolactin receptor, anticorps prolactin receptor L homeolog, anticorps prolactin receptor S homeolog, anticorps prolactin receptor a, anticorps PRLR, anticorps prlr.L, anticorps prlr.S, anticorps PR, anticorps prlr, anticorps Prlr, anticorps prlra
    Sujet
    PRLR (Prolactin Receptor) is a cytokine receptor. By somatic cell hybrid analysis and by in situ hybridization, Arden et al.(1989, 1990) demonstrated that the gene resides in the same chromosomal region as the growth hormone receptor (GHR) gene, which has been mapped to 5p13-p12. Cunningham et al.(1990) demonstrated that zinc greatly increases the affinity of GH for the extracellular binding domain of PRLR, although it is not required for binding of GH to GHR or for binding of prolactin to the prolactin receptor. By mutational analysis, they showed that a cluster of 3 residues(histidine-18, histidine-21, and glutamic acid-174) in GH and histidine-188 in PRLR (conserved in all PRLRs but not GHRs) are likely zinc-ion ligands.
    UniProt
    Q08501
    Pathways
    Signalistation JAK/STAT, Response to Growth Hormone Stimulus
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