SHBG anticorps (AA 30-210)

N° du produit ABIN3032554

Détail du produit anti-SHBG anticorps

Antigène: SHBG (Sex Hormone Binding Globulin (SHBG))

Épitope: AA 30-210

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHBG est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 30-210) was used as the immunogen for this SHBG antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the SHBG antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the SHBG antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur SHBG

Antigène: SHBG (Sex Hormone Binding Globulin (SHBG))

Autre désignation: SHBG (SHBG Produits)

Synonymes: anticorps ABP, anticorps SBP, anticorps TEBG, anticorps Abpa, anticorps shbgl, anticorps wu:fb66h07, anticorps wu:fd55b08, anticorps zgc:123063, anticorps shbg, anticorps sex hormone binding globulin, anticorps sex hormone-binding globulin, anticorps sex hormone binding globulin L homeolog, anticorps SHBG, anticorps Shbg, anticorps shbg, anticorps shbg.L

Sujet: Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to the sex hormones androgen and estrogen. SHBG is produced mostly by the liver and is released into the bloodstream. Other sites that produce it include the brain, uterus, testes, and placenta. It has both enhancing and inhibiting hormonal influences. It decreases with high levels of insulin, growth hormone, insulin-like growth factor 1 (IGF-1), androgens, prolactin and transcortin. High estrogen, andthyroxine cause it to increase. It has been found that the monosaccharides glucose and fructose reduced human SHBG production by hepatocytes, irrespective of the presence of insulin, by downregulation of hepatocyte nuclear factor-4A and replacement of HNF4A by COUP-TFI at a cis-element within the human SHBG promoter, coincident with repression of its transcriptional activity.

ID gène: 6462

Pathways: Hormone Transport