The stated application concentrations are suggested starting amounts. Titration of the SLC12A6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
-20 °C
Stockage commentaire
After reconstitution, the SLC12A6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Antigène
SLC12A6
(Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6))
anticorps Kcc3, anticorps ACCPN, anticorps KCC3, anticorps KCC3A, anticorps KCC3B, anticorps 9530023I19Rik, anticorps gaxp, anticorps solute carrier family 12, member 6, anticorps solute carrier family 12 member 6, anticorps Slc12a6, anticorps SLC12A6
Sujet
Solute carrier family 12 (potassium/chloride transporters) member 6, also called KCC3, is a protein that in humans is encoded by the SLC12A6 gene. This gene is a member of the K-Cl cotransporter(KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. By radiation hybrid and somatic cell hybrid analyses, this gene is mapped to 15q14. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.