TNFRSF1B anticorps (C-Term)

N° du produit ABIN3042335

Détail du produit anti-TNFRSF1B anticorps

Antigène: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Épitope: AA 288-318, C-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFRSF1B est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Fonction: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) detection. Tested with WB, FCM in Human,Rat.

Séquence: KKKPLCLQRE AKVPHLPADK ARGTQGPEQQ H

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) detection. Tested with WB, FCM in Human,Rat.
Gene Name: tumor necrosis factor receptor superfamily, member 1B
Protein Name: Tumor necrosis factor receptor superfamily member 1B

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human TNF Receptor II (288-318aa KKKPLCLQREAKVPHLPADKARGTQGPEQQH), different from the related mouse sequence by eleven amino acids, and from the related rat sequence by ten amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Flow Cytometry: Concentration:1-3 μg/1x106 cells, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-TNFRSF1B (ABIN3042335)

Zhou, He, Wang, Xie, Liu, Liu, Song, Ma: "Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therapy Using the Bifidobacterium-Mediated Recombinant HSV-1 Thymidine Kinase and Ganciclovir." dans: International journal of molecular sciences, Vol. 17, Issue 6, (2017) (PubMed).

Guan, Zheng, Huang, Li, Niu, Liu: "Powerful inner/outer controlled multi-target magnetic nanoparticle drug carrier prepared by liquid photo-immobilization." dans: Scientific reports, Vol. 4, pp. 4990, (2015) (PubMed).

Détails sur TNFRSF1B

Antigène: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Autre désignation: TNFRSF1B (TNFRSF1B Produits)

Synonymes: anticorps CD120b, anticorps TBPII, anticorps TNF-R-II, anticorps TNF-R75, anticorps TNFBR, anticorps TNFR1B, anticorps TNFR2, anticorps TNFR80, anticorps p75, anticorps p75TNFR, anticorps TNF-RII/TNFRSF1B, anticorps TNFR-II, anticorps TNFRSF1B, anticorps TNF-R2, anticorps TNF-alphaR2, anticorps TNFRII, anticorps TNFalpha-R2, anticorps Tnfr-1, anticorps Tnfr2, anticorps rank, anticorps zgc:163064, anticorps TNF receptor superfamily member 1B, anticorps tumor necrosis factor receptor superfamily, member 1b, anticorps tumor necrosis factor receptor superfamily, member 1B, anticorps TNFRSF1B, anticorps Tnfrsf1b, anticorps tnfrsf1b

Sujet: Tumor necrosis factor receptor 2 (TNFR2) is one of receptors of TNF. TNF has proinflammatory and immunosuppressive properties that may segregate at the level of the 2 TNF receptors (TNFRs), TNFR1 and TNFR2. The genes for TNFR1, a 55- kDa protein, and TNFR2, a 70- kDa protein, have been mapped to human chromosomes 12 (12pter-cen) and 1 (1pter-p32), respectively. TNFR2 was induced on glomerular endothelial cells of nephritic kidneys, and TNFR2 expression on intrinsic cells, but not leukocytes, was essential for glomerulonephritis and glomerular complement deposition. TNFR1 promotes systemic immune responses and renal T cell death, while intrinsic cell TNFR2 plays a critical role in complement-dependent tissue injury. Therefore, therapeutic blockade specifically of TNFR2 may be a promising strategy in the treatment of immune-mediated glomerulonephritis.

Synonyms: CD 120b antibody|CD120b antibody|CD120b antigen antibody|Etanercept antibody|p75 antibody| p75TNFR antibody|p80 TNF alpha receptor antibody|p80 TNF-alpha receptor antibody|TBP-2 antibody|TBP2 antibody|TBPII antibody|TNF R II antibody|TNF R2 antibody|TNF R75 antibody| TNF-R2 antibody|TNF-RII antibody|TNFBR antibody|TNFR 2 antibody|TNFR-II antibody|TNFR2 antibody|TNFR75 antibody|TNFR80 antibody|TNFRII antibody|TNFRSF 1B antibody|TNFRSF1B antibody|TNR1B antibody|TNR1B_HUMAN antibody|Tumor necrosis factor beta receptor antibody| Tumor necrosis factor binding protein 2 antibody|Tumor necrosis factor receptor 2 antibody| Tumor necrosis factor receptor superfamily member 1B precursor antibody|Tumor necrosis factor receptor type II antibody|Tumor necrosis factor-binding protein 2 antibody

ID gène: 7133

UniProt: P20333

Pathways: Signalisation NF-kappaB, Apoptose, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway