Tissue factor anticorps (AA 33-295)

N° du produit ABIN3042382

Détail du produit anti-Tissue factor anticorps

Antigène: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Épitope: AA 33-295

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tissue factor est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Tissue factor(F3) detection. Tested with WB in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Tissue factor(F3) detection. Tested with WB in Human.
Gene Name: coagulation factor III (thromboplastin, tissue factor)
Protein Name: Tissue factor

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Tissue Factor recombinant protein (Position: S33-S295). Human Tissue Factor shares 57.6% and 57.2% amino acid (aa) sequence identity with mouse and rat Tissue Factor, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-Tissue factor (ABIN3042382)

Li, Cao, Zeng, Liang, Xue, Xi, Zhou, Jiang: "Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis prevents lipopolysaccharide-induced apoptosis of pulmonary microvascular endothelial cells by inhibiting JNK/NF-?B pathways." dans: Scientific reports, Vol. 5, pp. 8209, (2015) (PubMed).

Li, Li, Li, Quan, Wang: "Cellular and molecular mechanisms underlying the action of ginsenoside Rg1 against Alzheimer's disease." dans: Neural regeneration research, Vol. 7, Issue 36, pp. 2860-6, (2014) (PubMed).

Guo, Qi, Yu, Du, Wu, Liu: "Effect of exenatide on the cardiac expression of adiponectin receptor 1 and NADPH oxidase subunits and heart function in streptozotocin-induced diabetic rats." dans: Diabetology & metabolic syndrome, Vol. 6, Issue 1, pp. 29, (2014) (PubMed).

Guo, Zhang, Li, Xu: "Effect of telmisartan on the expression of adiponectin receptors and nicotinamide adenine dinucleotide phosphate oxidase in the heart and aorta in type 2 diabetic rats." dans: Cardiovascular diabetology, Vol. 11, pp. 94, (2012) (PubMed).

Zhu, Lv, Chen, Wang, Zhong: "Protective effect and mechanism of sodium tanshinone II A sulfonate on microcirculatory disturbance of small intestine in rats with sepsis." dans: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 31, Issue 4, pp. 441-5, (2011) (PubMed).

Détails sur Tissue factor

Antigène: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Autre désignation: F3 (F3 Produits)

Sujet: Tissue factor also called platelet tissue factor, factor III, or CD142. This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.

Synonyms: CD142 antibody|CD142 antigen antibody|Coagulation factor III (thromboplastin tissue factor) antibody|Coagulation factor III antibody| F3 antibody|FLJ17960 antibody|TF antibody|TF_HUMAN antibody|TFA antibody|Thromboplastin antibody|Tissue factor antibody

ID gène: 2152

UniProt: P13726

Pathways: Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling