ATG7 anticorps (C-Term)

N° du produit ABIN3042570

Détail du produit anti-ATG7 anticorps

Antigène: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Épitope: AA 652-669, C-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG7 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Ubiquitin-like modifier-activating enzyme ATG7(ATG7) detection. Tested with WB in Human,Mouse,Rat.

Séquence: KVLDQYEREG FNFLAKVF

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Ubiquitin-like modifier-activating enzyme ATG7(ATG7) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: autophagy related 7
Protein Name: Ubiquitin-like modifier-activating enzyme ATG7

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Apg7(652-669aa KVLDQYEREGFNFLAKVF), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-ATG7 (ABIN3042570)

Shen, Li, Cai, Liu, Wang, Gan, Li, Wang, Sun, Deng, Liu, Li: "Erbin exerts a protective effect against inflammatory bowel disease by suppressing autophagic cell death." dans: Oncotarget, Vol. 9, Issue 15, pp. 12035-12049, (2018) (PubMed).

He, Wang, Han, Jin, Li, Wu, Ma, Cheng, Tang, Yang, Liu: "Nrf2 signalling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta." dans: Open biology, Vol. 6, Issue 7, (2017) (PubMed).

Détails sur ATG7

Antigène: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Autre désignation: ATG7 (ATG7 Produits)

Synonymes: anticorps APG7-LIKE, anticorps APG7L, anticorps GSA7, anticorps D8, anticorps UBA1B, anticorps UBE1L, anticorps UBE2, anticorps Ube1l, anticorps 1300004C08Rik, anticorps AO090001000744, anticorps atg7, anticorps 1810013K23Rik, anticorps Agp7, anticorps Apg7l, anticorps Atg7l, anticorps ATAPG7, anticorps ATATG7, anticorps ATG7, anticorps AUTOPHAGY 7, anticorps AUTOPHAGY-RELATED 7, anticorps K15I22.10, anticorps K15I22_10, anticorps autophagy related 7, anticorps ubiquitin like modifier activating enzyme 7, anticorps ubiquitin-like modifier activating enzyme 7, anticorps autophagy-related protein 7, anticorps Autophagy-related protein 7, anticorps Apg7p, anticorps ThiF family protein, anticorps ubiquitin-like conjugating enzyme Atg7, anticorps ATG7, anticorps UBA7, anticorps Uba7, anticorps ANI_1_3368024, anticorps AOR_1_1338164, anticorps PTRG_02236, anticorps PAAG_00287, anticorps PITG_12537, anticorps atg7, anticorps Atg7, anticorps APG7

Sujet: Autophagy-related protein 7 is a protein that in humans is encoded by the ATG7 gene. It is mapped to 3p25.3. This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein also shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. ATG7 is essential for the Apg12 conjugation system that mediates membrane fusion in autophagy. It is found that when nutrients are limited, ATG7 can regulate p53-dependent cell cycle and cell death pathways.

Synonyms: 1810013K23Rik antibody|Apg 7 antibody|APG7 autophagy 7 like antibody|APG7 autophagy 7-like(S. cerevisiae) antibody|APG7 like antibody|APG7, S. cerevisiae, homolog of antibody|APG7-like antibody|APG7L antibody|ATG 7 antibody|ATG12-activating enzyme E1 ATG7 antibody|atg7 antibody|ATG7 autophagy related 7 homolog(S. cerevisiae) antibody|ATG7 autophagy related 7 homolog antibody|Atg7l antibody|Autophagy 7, S. cerevisiae, homolog of antibody|Autophagy related protein 7 antibody|Autophagy-related 7(yeast) antibody|Autophagy-related protein 7 antibody|DKFZp434N0735 antibody|GSA 7 antibody|GSA7 antibody|hAGP7 antibody|Ubiquitin activating enzyme E1 like protein antibody|Ubiquitin-activating enzyme E1-like protein antibody|Ubiquitin-like modifier-activating enzyme ATG7 antibody

UniProt: O95352

Pathways: Response to Water Deprivation, Autophagy