GJB1 anticorps (Middle Region)

N° du produit ABIN3042611

Détail du produit anti-GJB1 anticorps

Antigène: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Épitope: AA 215-231, Middle Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GJB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Gap junction beta-1 protein(GJB1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: RACARRAQRR SNPPSRK

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Gap junction beta-1 protein(GJB1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: gap junction protein, beta 1, 32 kDa
Protein Name: Gap junction beta-1 protein

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human Connexin 32/GJB1(215-231aa RACARRAQRRSNPPSRK), identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GJB1

Antigène: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Autre désignation: GJB1 (GJB1 Produits)

Synonymes: anticorps GJIC, anticorps cmtx, anticorps cmtx1, anticorps connexin-30, anticorps connexin32, anticorps cx30, anticorps cx32, anticorps gja1, anticorps CX32, anticorps GJB1, anticorps AI118175, anticorps Cnx32, anticorps Cx32, anticorps Gjb-1, anticorps CMTX, anticorps CMTX1, anticorps gjb1-a, anticorps gap junction protein beta 1, anticorps connexin 32, anticorps probable serine/threonine-protein kinase CST, anticorps gap junction protein, beta 1, anticorps gap junction protein beta 1 L homeolog, anticorps gjb1, anticorps CX32, anticorps LOC9303136, anticorps GJB1, anticorps Gjb1, anticorps gjb1.L

Sujet: Connexins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells(Bergoffen et al., 1993). For a general discussion of connexin proteins, also known as Gap junction beta-1 protein. Gap junction beta-1 protein is a protein that in humans is encoded by the GJB1 gene. In melanocytic cells GJB1 gene expression may be regulated by MITF.

Synonyms: Charcot Marie Tooth neuropathy X linked antibody|CMTX 1 antibody|CMTX antibody|CMTX1 antibody|Connexin-32 antibody|Connexin32 antibody|CX 32 antibody|CX32 antibody|CXB1_HUMAN antibody|GAP junction 28 kDa liver protein antibody|Gap junction beta 1 protein antibody|Gap junction beta-1 protein antibody|Gap junction protein beta 1 32kD antibody|Gap junction protein beta 1 antibody|GJB 1 antibody|GJB1 antibody

UniProt: P08034

Pathways: Cell-Cell Junction Organization