IKBKG anticorps (N-Term)

N° du produit ABIN3042676

Détail du produit anti-IKBKG anticorps

Antigène: IKBKG (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))

Épitope: AA 1-15, N-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IKBKG est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for NF-kappa-B essential modulator(IKBKG) detection. Tested with WB in Mouse.

Séquence: MNKHPWKNQL SEMVQ

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for NF-kappa-B essential modulator(IKBKG) detection. Tested with WB in Mouse.
Gene Name: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Protein Name: NF-kappa-B essential modulator(NEMO)

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of mouse IKK gamma(1-15aa MNKHPWKNQLSEMVQ), different from the relative rat sequence by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur IKBKG

Antigène: IKBKG (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))

Autre désignation: IKBKG (IKBKG Produits)

Synonymes: anticorps AMCBX1, anticorps FIP-3, anticorps FIP3, anticorps Fip3p, anticorps IKK-gamma, anticorps IP, anticorps IP1, anticorps IP2, anticorps IPD2, anticorps NEMO, anticorps ZC2HC9, anticorps 1110037D23Rik, anticorps AI848108, anticorps AI851264, anticorps AW124339, anticorps IKK[g], anticorps Nemo, anticorps nemo, anticorps fj33c07, anticorps wu:fj33c07, anticorps zgc:113492, anticorps MGC97885, anticorps IKBKG, anticorps IKBKG_1, anticorps IKBKG_2, anticorps CG16910, anticorps DmIKK-gamma, anticorps DmIKKgamma, anticorps Dmel\\CG16910, anticorps Dmikkgamma, anticorps IKK, anticorps IKK[[gamma]], anticorps IKKg, anticorps IKKgamma, anticorps KEY, anticorps Kenny, anticorps Key, anticorps dIKK, anticorps dIKK-gamma, anticorps dmIKKgamma, anticorps inhibitor of nuclear factor kappa B kinase subunit gamma, anticorps inhibitor of kappaB kinase gamma, anticorps inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, anticorps inhibitor of nuclear factor kappa B kinase subunit gamma L homeolog, anticorps kenny, anticorps IKBKG, anticorps Ikbkg, anticorps ikbkg, anticorps ikbkg.L, anticorps IKBKG_1, anticorps key

Sujet: NF-kappa-B essential modulator (NEMO), also known as inhibitor of nuclear factor kappa-B kinase subunit gamma (IKK-γ), is a protein that in humans is encoded by the IKBKG gene. This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

Synonyms: IkB kinase associated protein 1 antibody|IkB kinase subunit gamma antibody|Inhibitor of nuclear factor kappa B kinase subunit gamma antibody|AMCBX1 antibody|FIP 3 antibody|FIP-3 antibody|FIP3 antibody|Fip3p antibody|I kappa B kinase gamma antibody|I-kappa-B kinase subunit gamma antibody|IkB kinase associated protein 1 antibody|IkB kinase gamma subunit antibody|IkB kinase subunit gamma antibody|IkB kinase-associated protein 1 antibody|IKBKG antibody|IKK-gamma antibody|IKKAP 1 antibody|IKKAP1 antibody|IKKG antibody|Incontinentia pigmenti antibody|Inhibitor of kappa light polypeptide gene enhancer in B cells kinase gamma antibody|Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma antibody|Inhibitor of nuclear factor kappa B kinase gamma subunit antibody|Inhibitor of nuclear factor kappa B kinase subunit gamma antibody|Inhibitor of nuclear factor kappa-B kinase subunit gamma antibody|IP 1 antibody|IP 2 antibody|IP antibody|IP1 antibody|IP2 antibody|IPD2 antibody|NEMO antibody|NEMO_HUMAN antibody|NF kappa B essential modifier antibody|NF kappa B essential modulator antibody|NF kappaB essential modifier antibody|NF kappaB essential modulator antibody|NF-kappa-B essential modifier antibody|NF-kappa-B essential modulator antibody|NFkappaB essential modulator antibody|ZC2HC9 antibody

UniProt: O88522

Pathways: Signalisation NF-kappaB, Signalisation RTK, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, M Phase, Production of Molecular Mediator of Immune Response, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins