CYP7A1 anticorps (AA 301-504)
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- Antigène Voir toutes CYP7A1 Anticorps
- CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))
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Épitope
- AA 301-504
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Reactivité
- Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CYP7A1 est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- Rabbit IgG polyclonal antibody for Cholesterol 7-alpha-monooxygenase(CYP7A1) detection. Tested with WB in Human,Mouse,Rat.
- Réactivité croisée (Details)
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Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Attributs du produit
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Rabbit IgG polyclonal antibody for Cholesterol 7-alpha-monooxygenase(CYP7A1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: cytochrome P450, family 7, subfamily A, polypeptide 1
Protein Name: Cholesterol 7-alpha-monooxygenase - Purification
- Immunogen affinity purified.
- Immunogène
- E.coli-derived human CYP7A1 recombinant protein (Position: M301-L504). Human CYP7A1 shares 85.2 % and 83.3% amino acid (aa) sequence identity with mouse and rat CYP7A1, respectively.
- Isotype
- IgG
- Top Product
- Discover our top product CYP7A1 Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Antigène
- CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))
- Autre désignation
- CYP7A1 (CYP7A1 Produits)
- Synonymes
- anticorps CP7A, anticorps CYP7, anticorps CYPVII, anticorps CHAP, anticorps CYP7S1, anticorps cyp7a1a, anticorps zgc:63920, anticorps cytochrome P450 family 7 subfamily A member 1, anticorps cytochrome P450, family 7, subfamily a, polypeptide 1, anticorps cytochrome P450, family 7, subfamily A, polypeptide 1, anticorps cholesterol 7-alpha-hydroxylase, anticorps CYP7A1, anticorps Cyp7a1, anticorps cyp7a1
- Sujet
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CYP7A1 (Cytochrome P450 Subfamily VIIA Polypeptide 1), also called CYP7 or CHOLESTEROL 7-ALPHA -HYDROXYLASE, is an enzyme that in humans is encoded by the CYP7A1 gene. Using both mouse-human somatic cell hybrids and in situ chromosomal hybridization, Cohen et al. (1992) mapped the CYP7 gene to 8q11-q12. By transfection of reporter constructs, mutation analysis, and DNase footprinting, Molowa et al. (1992) identified areas of the CYP7A1 promoter region that showed hepatocyte-specific activation. They found HNF3 to be an activator of CYP7A1 activity. Agellon et al. (2002) found that wildtype mice and mice transgenic for human CYP7A1 respond differently to cholesterol feeding. Cholesterol feeding stimulated Cyp7a1 mRNA abundance and enzymatic activity in wildtype mice, but repressed human CYP7A1 mRNA and activity in transgenic mice.
Synonyms: Cholesterol 7 alpha hydroxylase antibody|Cholesterol 7 alpha monooxygenase antibody| cholesterol 7 alpha-monooxygenase antibody|Cholesterol 7-alpha-hydroxylase antibody| Cholesterol 7-alpha-monooxygenase antibody|CP7A antibody|CP7A1_HUMAN antibody|CYP 7 antibody|CYP7 antibody|CYP7A1 antibody|CYPVII antibody|Cytochrome P450 7A1 antibody| cytochrome P450, family 7, subfamily A, polypeptide 1 antibody|Cytochrome P450, subfamily VIIA (cholesterol 7 alpha monooxygenase), antibody|cytochrome P450, subfamily VIIA (cholesterol 7 alpha-monooxygenase), antibody|Cytochrome P450, subfamily VIIA (cholesterol 7 alpha-monooxygenase), polypeptide 1 antibody|MGC126826 antibody|MGC138389 antibody - ID gène
- 1581
- UniProt
- P22680
- Pathways
- Steroid Hormone Biosynthesis, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha
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