ADAM10 anticorps (C-Term)

N° du produit ABIN3043163

Détail du produit anti-ADAM10 anticorps

Antigène: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Épitope: AA 612-627, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAM10 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Disintegrin and metalloproteinase domain-containing protein 10(ADAM10) detection. Tested with WB in Human.

Séquence: SVQWSRHFSG RTITLQ

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Disintegrin and metalloproteinase domain-containing protein 10(ADAM10) detection. Tested with WB in Human.
Gene Name: ADAM metallopeptidase domain 10
Protein Name: Disintegrin and metalloproteinase domain-containing protein 10(ADAM 10)

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human ADAM10(612-627aa SVQWSRHFSGRTITLQ).

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-ADAM10 (ABIN3043163)

Lin, Huang, Xie, Zhou, Yang, Huang: "Gemcitabine inhibits immune escape of pancreatic cancer by down regulating the soluble ULBP2 protein." dans: Oncotarget, Vol. 7, Issue 43, pp. 70092-70099, (2018) (PubMed).

Détails sur ADAM10

Antigène: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Autre désignation: ADAM10 (ADAM10 Produits)

Synonymes: anticorps ADAM10, anticorps Adam10, anticorps adam10, anticorps wu:fc03d12, anticorps ad10, anticorps cd156c, anticorps kuz, anticorps kuzbanian, anticorps madm, anticorps xadam10, anticorps ADAM-10, anticorps ADAM 10, anticorps AD10, anticorps CD156c, anticorps HsT18717, anticorps MADM, anticorps 1700031C13Rik, anticorps LOC100219653, anticorps zgc:64203, anticorps ADAM metallopeptidase domain 10, anticorps ADAM metallopeptidase domain 10a, anticorps ADAM metallopeptidase domain 10 S homeolog, anticorps a disintegrin and metallopeptidase domain 10, anticorps ADAM metallopeptidase domain 10b, anticorps ADAM10, anticorps Adam10, anticorps adam10a, anticorps adam10.S, anticorps adam10b

Sujet: ADAM10, A Disintegrin and Metalloproteinase Domain 10, is also know as AD10. ADAM10 is a member of the ADAM family and members of this family are cell surface proteins with a unique structure possessing both potential adhesion and protease function. The ADAM10 gene is mapped to chromosome 15q21.3-q23. ADAM proteins contain an N-terminal signal sequence, followed by a prodomain, a metalloprotease-like domain, a disintegrin-like domain, a cysteine-rich region, an EGF -like repeat, a transmembrane domain, and a C-terminal cytoplasmic tail. Conversion of the membrane-bound precursor to a secreted mature protein is mediated by a protease termed TNFA convertase. ADAM10 possesses TNFA convertase activity.

Synonyms: A disintegrin and metalloprotease domain 10 antibody|A disintegrin and metalloproteinase domain 10 antibody|AD 10 antibody|AD10 antibody|ADA10_HUMAN antibody|ADAM 10 antibody|ADAM metallopeptidase domain 10 antibody|ADAM10 antibody|CD 156c antibody|CD156c antibody|CD156c antigen antibody|CDw156 antibody|disintegrin and metalloproteinase domain containing protein 10 antibody|Disintegrin and metalloproteinase domain-containing protein 10 antibody|HsT 18717 antibody|HsT18717 antibody|Kuz antibody|Kuzbanian antibody|Kuzbanian protein homolog antibody|MADM antibody|Mammalian disintegrin metalloprotease antibody|Mammalian disintegrin-metalloprotease antibody

UniProt: O14672

Pathways: Signalisation Notch, EGFR Signaling Pathway