Caspase 7 anticorps (Middle Region)

N° du produit ABIN3043217

Détail du produit anti-Caspase 7 anticorps

Antigène: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Épitope: AA 237-255, Middle Region

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Caspase-7(CASP7) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: RGSWFVQALC SILEEHGKD

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Caspase-7(CASP7) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: caspase 7, apoptosis-related cysteine peptidase
Protein Name: Caspase-7(CASP-7)

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human Caspase-7(P11)(237-255aa RGSWFVQALCSILEEHGKD), different from the related mouse and rat sequences by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Caspase 7

Antigène: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Autre désignation: CASP7 (CASP7 Produits)

Synonymes: anticorps xCaspase-7, anticorps caspase-7, anticorps caspase7, anticorps cmh-1, anticorps ice-lap3, anticorps mch3, anticorps CASP7, anticorps AI314680, anticorps CMH-1, anticorps ICE-IAP3, anticorps Mch3, anticorps mCASP-7, anticorps CASP-7, anticorps ICE-LAP3, anticorps LICE2, anticorps MCH3, anticorps Caspase-7, anticorps MCH3/SCA-2, anticorps SCA-2, anticorps caspase 7, anticorps caspase-7, anticorps caspase 7 S homeolog, anticorps CASP7, anticorps xcaspase-7, anticorps casp7, anticorps casp7.S, anticorps Casp7

Sujet: CASP7, Caspase-7, apoptosis-related cysteine peptidase, is a human protein encoded by the CASP7 gene. CASP7 orthologs have been identified in nearly all mammals for which complete genome data are available. CASP7 is a member of the caspase(cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis. Using radiation hybrid mapping, the CASP7 gene was localized to human chromosome 10q25.1-q25.2. The orderly activation of CASP7 regulates microglia activation through a protein kinase C-delta(PRKCD)-dependent pathway.

Synonyms: Apoptosis related cysteine peptidase antibody|Apoptosis Related Cysteine Protease antibody|Apoptotic protease Mch-3 antibody|Apoptotic Protease MCH3 antibody|CASP 7 antibody|CASP-7 antibody|CASP7 antibody|Caspase-7 subunit p11 antibody|Caspase7 antibody|CMH 1 antibody|CMH-1 antibody|CMH1 antibody|ICE LAP3 antibody|ICE like Apoptotic Protease 3 antibody|ICE-LAP3 antibody|ICE-like apoptotic protease 3 antibody|MCH3 antibody

UniProt: P55210

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity