ITCH anticorps (Middle Region)

N° du produit ABIN3043253

Détail du produit anti-ITCH anticorps

Antigène: ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))

Épitope: AA 410-437, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITCH est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase Itchy homolog(ITCH) detection. Tested with WB in Human.

Séquence: AMQQFNQRFI YGNQDLFATS QSKEFDPL

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase Itchy homolog(ITCH) detection. Tested with WB in Human.
Gene Name: itchy E3 ubiquitin protein ligase
Protein Name: E3 ubiquitin-protein ligase Itchy homolog

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human ITCH/AIP4 (410-437aa AMQQFNQRFIYGNQDLFATSQSKEFDPL), different from the related mouse sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur ITCH

Antigène: ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))

Autre désignation: ITCH (ITCH Produits)

Synonymes: anticorps AIF4, anticorps AIP4, anticorps NAPP1, anticorps dJ468O1.1, anticorps 6720481N21Rik, anticorps 8030492O04Rik, anticorps A130065M08, anticorps C230047C07Rik, anticorps itchy E3 ubiquitin protein ligase, anticorps itchy, E3 ubiquitin protein ligase, anticorps ITCH, anticorps Itch

Sujet: ITCH is an ubiquitin-conjugating enzyme. This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms: AIF4 antibody|AIP4 antibody|Atrophin 1 interacting protein 4 antibody|Atrophin-1-interacting protein 4 antibody|dJ468O1.1 antibody|dJ468O1.1 (atrophin 1 interacting protein 4 (AIP4)) antibody|dJ468O1.1 atrophin 1 interacting protein 4 AIP4 antibody|E3 ubiquitin protein ligase Itchy homolog antibody|E3 ubiquitin-protein ligase Itchy homolog antibody|EC 6.3.2 antibody|Itch antibody|ITCH_HUMAN antibody|Itchy E3 ubiquitin protein ligase antibody|Itchy E3 ubiquitin protein ligase homolog antibody|Itchy E3 ubiquitin protein ligase homolog mouse antibody|Itchy E3 ubiquitin protein ligase, mouse, homolog of antibody|itchy homolog E3 ubiquitin protein ligase antibody|Itchy mouse homolog E3 ubiquitin protein ligase antibody|NAPP1 antibody|NFE2 associated polypeptide 1 antibody| NFE2-associated polypeptide 1 antibody|Ubiquitin protein ligase ITCH antibody

ID gène: 83737

UniProt: Q96J02

Pathways: Activation of Innate immune Response, CXCR4-mediated Signaling Events