ITGA5 anticorps (AA 787-992)

N° du produit ABIN3043256

Détail du produit anti-ITGA5 anticorps

Antigène: ITGA5 (Integrin, alpha 5 (ITGA5))

Épitope: AA 787-992

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA5 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Fonction: Rabbit IgG polyclonal antibody for Integrin alpha-5(ITGA5) detection. Tested with WB, FCM in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Integrin alpha-5(ITGA5) detection. Tested with WB, FCM in Human,Mouse,Rat.
Gene Name: integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Protein Name: Integrin alpha-5

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Integrin alpha 5 recombinant protein (Position: E787-E992). Human Integrin alpha 5 shares 86% amino acid (aa) sequence identity with mouse Integrin alpha 5.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Integrin alpha 5 is approximately 0.25 ng/lane under reducing conditions.
Flow Cytometry: Concentration:1-3 μg/1x106 cells, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-ITGA5 (ABIN3043256)

Chen, Sun, Liu, Tong, Meng: "Silencing of Paternally Expressed Gene 10 Inhibits Trophoblast Proliferation and Invasion." dans: PLoS ONE, Vol. 10, Issue 12, pp. e0144845, (2015) (PubMed).

Zhang, Ren, Luo, Fan, Liu, Liang, Ma, Yu, Bai: "A small physiological electric field mediated responses of extravillous trophoblasts derived from HTR8/SVneo cells: involvement of activation of focal adhesion kinase signaling." dans: PLoS ONE, Vol. 9, Issue 3, pp. e92252, (2014) (PubMed).

Huang, Lian, Chen, Yang, Yang: "Characterization of rat hair follicle stem cells selected by vario magnetic activated cell sorting system." dans: Acta histochemica et cytochemica, Vol. 42, Issue 5, pp. 129-36, (2009) (PubMed).

Détails sur ITGA5

Antigène: ITGA5 (Integrin, alpha 5 (ITGA5))

Autre désignation: ITGA5 (ITGA5 Produits)

Synonymes: anticorps ITGA5, anticorps Cd49e, anticorps Fnra, anticorps VLA5, anticorps CD49e, anticorps FNRA, anticorps VLA5A, anticorps Itga5_retired, anticorps integrin subunit alpha 5, anticorps integrin alpha 5 (fibronectin receptor alpha), anticorps ITGA5, anticorps Itga5

Sujet: Integrin alpha-5, also known as FNRA or VLA5A, is a protein that in humans is encoded by the ITGA5 gene. The product of this gene belongs to the integrin alpha chain family. Integrins are integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Synonyms: CD49 antigen-like family member E antibody|CD49e antibody|Fibronectin Receptor alpha antibody|Fibronectin receptor subunit alpha antibody|Fibronectin receptor, alpha subunit antibody|FNRA antibody|Integrin alpha 5 (fibronectin receptor alpha) antibody|Integrin alpha-5 antibody|Integrin alpha-5 light chain antibody|Integrin alpha-F antibody|Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) antibody|ITA5_HUMAN antibody|ITGA 5 antibody|ITGA5 antibody|Very Late Activation Protein 5 alpha antibody|Very late activation protein 5, alpha subunit antibody|VLA-5 antibody|VLA5 antibody|VLA5A antibody

ID gène: 3678

UniProt: P08648

Pathways: Integrin Complex