EDNRB anticorps (C-Term)
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- Antigène Voir toutes EDNRB Anticorps
- EDNRB (Endothelin Receptor Type B (EDNRB))
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Épitope
- AA 406-439, C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EDNRB est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Rabbit IgG polyclonal antibody for Endothelin B receptor(EDNRB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Séquence
- QSFEEKQSLE EKQSCLKFKA NDHGYDNFRS SNKY
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Endothelin B receptor(EDNRB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: endothelin receptor type B
Protein Name: Endothelin B receptor - Purification
- Immunogen affinity purified.
- Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of human EDNRB (406-439aa QSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKY), different from the related mouse and rat sequences by one amino acid.
- Isotype
- IgG
- Top Product
- Discover our top product EDNRB Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Antigène
- EDNRB (Endothelin Receptor Type B (EDNRB))
- Autre désignation
- EDNRB (EDNRB Produits)
- Synonymes
- anticorps ABCDS, anticorps ET-B, anticorps ET-BR, anticorps ETB, anticorps ETBR, anticorps ETRB, anticorps HSCR, anticorps HSCR2, anticorps WS4A, anticorps Ednra, anticorps Etb, anticorps ETR-b, anticorps ETb, anticorps Sox10m1, anticorps EDNRB, anticorps abcds, anticorps etb, anticorps etrb, anticorps hscr, anticorps hscr2, anticorps endothelin receptor type B, anticorps EDNRB, anticorps Ednrb, anticorps ednrb
- Sujet
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Endothelin receptor type B, also known as ETB is a protein that in humans is encoded by the EDNRB gene. The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: ABCDS antibody|Ednra antibody|Ednrb antibody|EDNRB_HUMAN antibody|Endothelin B receptor antibody|Endothelin B receptor precursor antibody|Endothelin receptor Non selective type antibody|Endothelin receptor non-selective type antibody|Endothelin receptor type B antibody|ET B antibody|ET-B antibody|ET-BR antibody|ETB antibody|ETBR antibody|ETRB antibody|Hirschsprung disease 2 antibody|HSCR antibody|HSCR2 antibody|OTTHUMP00000018534 antibody|OTTHUMP00000178736 antibody|WS4A antibody - ID gène
- 1910
- UniProt
- P24530
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process
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