SERPINB5 anticorps (AA 1-350)

N° du produit ABIN3043330

Détail du produit anti-SERPINB5 anticorps

Antigène: SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))

Épitope: AA 1-350

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SERPINB5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Fonction: Rabbit IgG polyclonal antibody for Serpin B5(SERPINB5) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Serpin B5(SERPINB5) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: serpin peptidase inhibitor, clade B (ovalbumin), member 5
Protein Name: Serpin B5

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MASPIN recombinant protein (Position: M1-A350). Human MASPIN shares 88% and 89% amino acid (aa) sequence identity with mouse and rat MASPIN, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for MASPIN is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-SERPINB5 (ABIN3043330)

Zhang, Qi, Cao, Zu, Chen: "Expression and clinical significance of microRNA-21, maspin and vascular endothelial growth factor-C in bladder cancer." dans: Oncology letters, Vol. 10, Issue 4, pp. 2610-2616, (2015) (PubMed).

Yang, Shi, Li, Yi: "Effects of shRNA targeting maspin on invasion of gastric carcinoma SGC7901 cell line." dans: Oncology reports, Vol. 25, Issue 1, pp. 259-65, (2010) (PubMed).

Détails sur SERPINB5

Antigène: SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))

Autre désignation: SERPINB5 (SERPINB5 Produits)

Synonymes: anticorps 1110036M19Rik, anticorps AI462524, anticorps AI646751, anticorps Maspin, anticorps PI-5, anticorps Spi7, anticorps ovalbumin, anticorps PI5, anticorps maspin, anticorps Pi5, anticorps serine (or cysteine) peptidase inhibitor, clade B, member 5, anticorps serpin family B member 5, anticorps serpin peptidase inhibitor, clade B (ovalbumin), member 5 S homeolog, anticorps Serpinb5, anticorps SERPINB5, anticorps serpinb5.S

Sujet: SERPINB5 is also known as PI5 or maspin. Maspin (mammary serine protease inhibitor) is a protein that in humans is encoded by the SERPINB5 gene. Maspin is expressed in the skin, prostate, testis, intestine, tongue, lung, and the thymus. Maspin is a member of the serpin superfamily of serine protease inhibitors.[1] The primary function of most members of this family is to regulate the breakdown of proteins by inhibiting the catalytic activity of proteinases. Through this mechanism of action, serpins regulate a number of cellular processes includingphagocytosis, coagulation, and fibrinolysis.

Synonyms: mammary serine proteinase inhibitor antibody|Maspin antibody|Ovalbumin antibody|Peptidase inhibitor 5 antibody|PI-5 antibody|PI5 antibody|Protease inhibitor 5 antibody|Serine (or cysteine) peptidase inhibitor, clade B, member 5 antibody|Serpin B5 antibody|serpin peptidase inhibitor antibody|Serpin peptidase inhibitor, clade B (ovalbumin), member 5 antibody|SERPINB5 antibody|SPB5_HUMAN antibody|Spi5 antibody|Spi7 antibody

ID gène: 5268

UniProt: P36952

Pathways: Signalisation p53