P2RX4 anticorps (AA 262-388)

N° du produit ABIN3043376

Détail du produit anti-P2RX4 anticorps

Antigène: P2RX4 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4))

Épitope: AA 262-388

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P2RX4 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for P2X purinoceptor 4(P2RX4) detection. Tested with WB in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for P2X purinoceptor 4(P2RX4) detection. Tested with WB in Human.
Gene Name: purinergic receptor P2X, ligand gated ion channel, 4
Protein Name: P2X purinoceptor 4

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human P2RX4 recombinant protein (Position: N262-Q388). Human P2RX4 shares 91% and 90% amino acid (aa) sequence identity with mouse and rat P2RX4, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for P2RX4 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur P2RX4

Antigène: P2RX4 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4))

Autre désignation: P2RX4 (P2RX4 Produits)

Sujet: Purinoceptor P2X4, also called P2X4R is a protein that in humans is encoded by the P2RX4 gene. This gene belongs to the family of purinoceptors for ATP. P2RX4 was mapped to 12q24.32 by fluorescence in situ hybridization. P2RX4 is a receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin. P2X4 receptor in hyperactive microglia is necessary for tactile allodynia after nerve injury and is sufficient to produce tactile allodynia in normal animals. P2X4 recetors have beeb implicated in the regulation of cardiac function, ATP-mediated cell death, synaptic strengthening, and activating of the inflammasome in response to injury.

Synonyms: AI504491 antibody|ATP gated cation channel protein antibody|ATP receptor antibody|AW555605 antibody|D5Ertd444e antibody|MGC143034 antibody|OTTMUSP00000023741 antibody|OTTMUSP00000023745 antibody|OTTMUSP00000023746 antibody|OTTMUSP00000023747 antibody|p2rx4 antibody|P2RX4_HUMAN antibody|P2X purinoceptor 4 antibody|P2X receptor subunit 4 antibody|P2X4 antibody|P2X4R antibody|Purinergic receptor antibody|Purinergic receptor P2X ligand gated ion channel 4 antibody|Purinergic receptor P2X4 antibody|Purinoceptor P2X4 antibody

ID gène: 5025

UniProt: Q99571

Pathways: Synaptic Membrane