PTPN2 anticorps (AA 1-330)

N° du produit ABIN3043447

Détail du produit anti-PTPN2 anticorps

Antigène: PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))

Épitope: AA 1-330

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPN2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Tyrosine-protein phosphatase non-receptor type 2(PTPN2) detection. Tested with WB, IHC-P in Human,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Tyrosine-protein phosphatase non-receptor type 2(PTPN2) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: protein tyrosine phosphatase, non-receptor type 2
Protein Name: Tyrosine-protein phosphatase non-receptor type 2

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TCPTP recombinant protein (Position: M1-C330). Human TCPTP shares 91.4% and 92% amino acid (aa) sequence identity with mouse and rat TCPTP, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur PTPN2

Antigène: PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))

Autre désignation: PTPN2 (PTPN2 Produits)

Synonymes: anticorps PTN2, anticorps PTPT, anticorps TC-PTP, anticorps TCELLPTP, anticorps TCPTP, anticorps AI325124, anticorps Ptpt, anticorps PTP-1B, anticorps cb806, anticorps ptpn2, anticorps ptpn2l, anticorps wu:fc10h07, anticorps zgc:55339, anticorps zgc:76973, anticorps hm:zeh1546, anticorps zgc:63623, anticorps ptn2, anticorps ptpt, anticorps tc-ptp, anticorps tcellptp, anticorps tcptp, anticorps protein tyrosine phosphatase, non-receptor type 2, anticorps protein tyrosine phosphatase, non-receptor type 2 S homeolog, anticorps protein tyrosine phosphatase, non-receptor type 2, b, anticorps protein tyrosine phosphatase, non-receptor type 2, a, anticorps protein tyrosine phosphatase, non-receptor type 2 L homeolog, anticorps PTPN2, anticorps Ptpn2, anticorps ptpn2.S, anticorps ptpn2b, anticorps ptpn2a, anticorps ptpn2.L

Sujet: TCPTP is also called as PTPN2. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported.

Synonyms: Protein tyrosine phosphatase non receptor type 2 antibody|PTN2 antibody|PTN2_HUMAN antibody|PTPN 2 antibody|PTPN2 antibody|PTPT antibody|T cell protein tyrosine phosphatase antibody|T-cell protein-tyrosine phosphatase antibody|TC PTP antibody|TCELLPTP antibody| TCPTP antibody|Tyrosine protein phosphatase non receptor type 2 antibody|Tyrosine-protein phosphatase non-receptor type 2 antibody

ID gène: 5771

UniProt: P17706

Pathways: EGFR Signaling Pathway, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling