TRPC7 anticorps (AA 716-862)

N° du produit ABIN3043494

Cet anticorps anti-TRPC7 est un anticorps Lapin Polyclonal détectant TRPC7 dans WB. Adapté pour Humain et Souris. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour TRPC7 anticorps (AA 716-862) (ABIN3043494)

Antigène: TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPC7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRPC7 anticorps

Épitope: AA 716-862

Fonction: Anti-TRP 7/TRPC7 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-TRP 7/TRPC7 Antibody Picoband® (ABIN3043494). Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TRP 7 recombinant protein (Position: K716-I862). Human TRP 7 shares 95% amino acid (aa) sequence identity with mouse TRP 7.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse
1. Du, J., Xie, J., Yue, L. Intracellular calcium activates TRPM2 and its alternative spliced isoforms. Proc. Nat. Acad. Sci. 106: 7239-7244, 2009. 2. Farooqi, A. A., Javeed, M. K., Javed, Z., Riaz, A. M., Mukhtar, S., Minhaj, S., Abbas, S., Bhatti, S. TRPM channels: same ballpark, different players, and different rules in immunogenetics. Immunogenetics 63: 773-787, 2011. 3. McQuillin, A., Bass, N. J., Kalsi, G., Lawrence, J., Puri, V., Choudhury, K., Detera-Wadleigh, S. D., Curtis, D., Gurling, H. M. D. Fine mapping of a susceptibility locus for bipolar and genetically related unipolar affective disorders, to a region containing the C21ORF29 and TRPM2 genes on chromosome 21q22.3. Molec. Psychiat. 11: 134-142, 2006.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Références pour anticorps anti-TRPC7 (ABIN3043494)

Wang, Wang, Li: "TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells." dans: Oncotarget, Vol. 7, Issue 32, pp. 50937-50951, (2018) (PubMed).

Détails sur TRPC7

Antigène: TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))

Autre désignation: TRPC7

Sujet:

Synonyms: Short transient receptor potential channel 7,TrpC7,Transient receptor protein 7,TRP-7,hTRP7,TRPC7,TRP7,

Tissue Specificity: Expressed in brain with higher levels in fetal brain. Found in cerebellum and occipital pole. .

Background: Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a human gene encoding a protein of the same name. Using a cosmid/BAC contig, this gene is mapped to chromosome 21q22.3. TRPC7 is the most abundantly expressed long TRPC in peripheral blood and in some blood cell lines. The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death.

Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC7 sub-subfamily.

Poids moléculaire: 99 kDa

ID gène: 57113