ABCB4 anticorps (AA 601-720)

N° du produit ABIN3043734

Détail du produit anti-ABCB4 anticorps

Antigène: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Épitope: AA 601-720

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCB4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Phosphatidylcholine translocator ABCB4(ABCB4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Phosphatidylcholine translocator ABCB4(ABCB4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: ATP-binding cassette, sub-family B (MDR/TAP), member 4
Protein Name: Phosphatidylcholine translocator ABCB4

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ABCB4 recombinant protein (Position: A601-A720). Human ABCB4 shares 79% amino acid (aa) sequence identity with both mouse and rat ABCB4.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for ABCB4 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur ABCB4

Antigène: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Autre désignation: ABCB4 (ABCB4 Produits)

Synonymes: anticorps ABC21, anticorps GBD1, anticorps ICP3, anticorps MDR2, anticorps MDR2/3, anticorps MDR3, anticorps PFIC-3, anticorps PGY3, anticorps zgc:172149, anticorps Mdr2, anticorps Pgy-2, anticorps Pgy2, anticorps mdr-2, anticorps Pgy3, anticorps ABCB4a, anticorps DEFB1, anticorps PGP2, anticorps PGY2, anticorps PGP3, anticorps ABCB4, anticorps RUNDC3B, anticorps ATP binding cassette subfamily B member 4, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 4, anticorps beta-defensin 1-like, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 1B, anticorps RUN domain-containing protein 3B, anticorps ABCB4, anticorps abcb4, anticorps Abcb4, anticorps LOC100861170, anticorps Abcb1b, anticorps LOC101122517

Sujet: Adenosine triphosphate-binding cassette subfamily B, member 4 (ABCB4), also called MDR3, is a protein that in humans is encoded by the ABCB4 gene. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. The ABCB4 gene contains 28 exons and 27 of these contain coding sequences for the two homologous halves of the protein that correlate with functional domains. ABCB4 gene mutations represent a genetic factor involved in this peculiar form of cholesterol gallstone disease in adults.

Synonyms: ABC 21 antibody|ABC B4 antibody|ABC21 antibody|ABCB 4 antibody|Abcb4 antibody|ABCB4 protein antibody|ATP binding cassette sub family B MDR/TAP member 4 antibody|ATP binding cassette sub family B member 4 antibody|ATP-binding cassette sub-family B member 4 antibody|MDR 3 antibody|MDR2 antibody|MDR2/3 antibody|MDR3 antibody|MDR3 P glycoprotein antibody|MDR3 P gp antibody|MDR3_HUMAN antibody|Multidrug resistance protein 3 antibody|Multiple drug resistance 3 antibody|P glycoprotein 3 antibody|P-glycoprotein 3 antibody|PFIC 3 antibody|PFIC3 antibody|PGY 3 antibody|PGY3 antibody

ID gène: 5244

UniProt: P21439

Pathways: Regulation of Lipid Metabolism by PPARalpha