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Glutamate Receptor 1 anticorps (AA 19-360)

GLUR1 Reactivité: Humain, Rat, Souris WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3043837
  • Antigène Voir toutes Glutamate Receptor 1 (GLUR1) Anticorps
    Glutamate Receptor 1 (GLUR1)
    Épitope
    • 17
    • 17
    • 15
    • 15
    • 13
    • 13
    • 13
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 19-360
    Reactivité
    • 112
    • 111
    • 93
    • 11
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 123
    • 26
    • 1
    Lapin
    Clonalité
    • 112
    • 38
    Polyclonal
    Conjugué
    • 74
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Glutamate Receptor 1 est non-conjugé
    Application
    • 102
    • 40
    • 40
    • 40
    • 38
    • 28
    • 16
    • 15
    • 13
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit IgG polyclonal antibody for Glutamate receptor 1(GRIA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Glutamate receptor 1(GRIA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: glutamate receptor, ionotropic, AMPA 1
    Protein Name: Glutamate receptor 1
    Purification
    Immunogen affinity purified.
    Immunogène
    E.coli-derived human GRIA1 recombinant protein (Position: A19-R360). Human GRIA1 shares 98% amino acid (aa) sequence identity with both mouse and rat GRIA1.
    Isotype
    IgG
    Top Product
    Discover our top product GLUR1 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for GRIA1 is approximately 0.25 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Liu, Mei, Li, Roboti, Pang, Ying, Gao, Lowe, Bao: "Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 2, pp. 346-351, (2018) (PubMed).

  • Antigène
    Glutamate Receptor 1 (GLUR1)
    Autre désignation
    GRIA1 (GLUR1 Produits)
    Synonymes
    anticorps GLUH1, anticorps GLUR1, anticorps GLURA, anticorps GluA1, anticorps HBGR1, anticorps gluR-A, anticorps 2900051M01Rik, anticorps Glr-1, anticorps Glr1, anticorps GluR-A, anticorps GluRA, anticorps Glur-1, anticorps Glur1, anticorps HIPA1, anticorps gluR-K1, anticorps GRIA1, anticorps glur1, anticorps Gria1, anticorps glur1b, anticorps gria1.2, anticorps sb:eu293, anticorps ZfGluR1a, anticorps glur1a, anticorps gria1.1, anticorps zfGRIA1[a], anticorps glutamate ionotropic receptor AMPA type subunit 1, anticorps glutamate receptor, ionotropic, AMPA1 (alpha 1), anticorps glutamate receptor, ionotropic, AMPA 1, anticorps glutamate receptor, ionotropic, AMPA 1 L homeolog, anticorps GluR1 protein, anticorps Glutamate receptor 1, anticorps glutamate receptor, ionotropic, AMPA 1b, anticorps glutamate receptor, ionotropic, AMPA 1a, anticorps GRIA1, anticorps Gria1, anticorps gria1, anticorps gria1.L, anticorps glur1, anticorps glr-1, anticorps gria1b, anticorps gria1a
    Sujet
    GLUR1, Glutamate receptor 1, is a protein that in humans is encoded by the GLUR1 gene. GLUR1 mRNA is widely expressed in human brain. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Each of the members (GRIA1-4) include flip and flop isoforms generated by alternative RNA splicing. The receptor subunits encoded by each isoform vary in their signal transduction properties. The isoform presented here is the flop isoform. In situ hybridization experiments showed that human GRIA1 mRNA is present in granule and pyramidal cells in the hippocampal formation.

    Synonyms: GLUR 1 antibody|GLUR A antibody|AMPA 1 antibody|AMPA selective glutamate receptor 1 antibody|AMPA-selective glutamate receptor 1 antibody|GluA1 antibody|GLUH 1 antibody|GLUH1 antibody|GluR K1 antibody|GluR-1 antibody|GluR-A antibody|GluR-K1 antibody|GLUR1 antibody|GLURA antibody|GluRK1 antibody|Glutamate receptor 1 antibody|Glutamate receptor ionotropic AMPA 1 antibody|Glutamate receptor ionotropic antibody|Glutamate receptor, ionotropic, AMPA 1 antibody|Gria 1 antibody|Gria1 antibody|GRIA1_HUMAN antibody|HBGR1 antibody|MGC133252 antibody|OTTHUMP00000160643 antibody|OTTHUMP00000165781 antibody|OTTHUMP00000224241 antibody|OTTHUMP00000224242 antibody|OTTHUMP00000224243 antibody
    ID gène
    2890
    UniProt
    P42261
    Pathways
    Signalisation PI3K-Akt
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