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GLUT1 anticorps (AA 92-492)

SLC2A1 Reactivité: Humain, Souris, Rat WB, ICC, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3043927
  • Antigène Voir toutes GLUT1 (SLC2A1) Anticorps
    GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))
    Épitope
    • 12
    • 9
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 92-492
    Reactivité
    • 82
    • 47
    • 46
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 68
    • 11
    • 5
    Lapin
    Clonalité
    • 57
    • 27
    Polyclonal
    Conjugué
    • 55
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp GLUT1 est non-conjugé
    Application
    • 56
    • 36
    • 31
    • 18
    • 17
    • 15
    • 11
    • 10
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Fonction
    Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 1(SLC2A1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 1(SLC2A1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
    Gene Name: solute carrier family 2 (facilitated glucose transporter), member 1
    Protein Name: Solute carrier family 2, facilitated glucose transporter member 1
    Purification
    Immunogen affinity purified.
    Immunogène
    E.coli-derived human SLC2A1 recombinant protein (Position: R92-V492). Human SLC2A1 shares 98% and 98.3% amino acid (aa) sequence identity with mouse and rat SLC2A1, respectively.
    Isotype
    IgG
    Top Product
    Discover our top product SLC2A1 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SLC2A1 is approximately 0.1 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) , IHC(F) and ICC.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Li, Zhao, Qi, Wang, Zhang, Li, Qin: "lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma." dans: International journal of oncology, Vol. 53, Issue 2, pp. 551-566, (2018) (PubMed).

  • Antigène
    GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))
    Autre désignation
    SLC2A1 (SLC2A1 Produits)
    Synonymes
    anticorps DYT17, anticorps DYT18, anticorps DYT9, anticorps EIG12, anticorps GLUT, anticorps GLUT1, anticorps GLUT1DS, anticorps HTLVR, anticorps PED, anticorps Glut-1, anticorps Glut1, anticorps GLUTB, anticorps GTG1, anticorps Gtg3, anticorps RATGTG1, anticorps SLC2A1, anticorps GLT1, anticorps GLUCOSE TRANSPORTER 1, anticorps T21H19.70, anticorps T21H19_70, anticorps plastidic GLC translocator, anticorps glut1, anticorps ped, anticorps slc2a1, anticorps slc2a14, anticorps solute carrier family 2 member 1, anticorps solute carrier family 2 (facilitated glucose transporter), member 1, anticorps plastidic GLC translocator, anticorps solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog, anticorps SLC2A1, anticorps Slc2a1, anticorps PGLCT, anticorps slc2a1.L
    Sujet
    GLUT1, also known as SLC2A1, is a major glucose transporter in the mammalian blood-brain barrier whose gene is mapped to 1p35-p31.3 and contains 10 exons. It is present at high levels in primate erythrocytes and brain endothelial cells. Not only can transport dehydroascorbic acid (the oxidized form of vitamin C) into the brain, GLUT1 is also likely to contribute to HTLV-associated disorders through interacting with HTLV envelope glycoproteins. Functionally, GLUT1 deficiency causes a decrease in embryonic glucose uptake and apoptosis, which may be involved in diabetic embryopathy, by contrast, an increased expression of GLUT1 in some malignant tumors may suggest a role for glucose-derivative tracers to detect in vivo thyroid cancer metastases by positron-emission tomography scanning.

    Synonyms: DYT17 antibody|DYT18 antibody|erythrocyte/brain antibody|Erythrocyte/brain HepG2 glucose transporter antibody|Erythrocyte/hepatoma glucose transporter antibody|facilitated glucose transporter member 1 antibody|Glucose transporter 1 antibody|Glucose transporter type 1 antibody|Glucose transporter type 1 erythrocyte/brain antibody|Glucose transporter type 1, erythrocyte/brain antibody|GLUT antibody|GLUT-1 antibody|GLUT1 antibody|GLUT1DS antibody| GLUTB antibody|GT1 antibody|GTG1 antibody|Gtg3 antibody|GTR1_HUMAN antibody|HepG2 glucose transporter antibody|MGC141895 antibody|MGC141896 antibody|PED antibody|RATGTG1 antibody| SLC2A 1 antibody|SLC2A1 antibody|Solute carrier family 2 (facilitated glucose transporter), member 1 antibody|Solute carrier family 2 antibody|Solute carrier family 2 facilitated glucose transporter member 1 antibody|Solute carrier family 2, facilitated glucose transporter member 1 antibody
    ID gène
    6513
    UniProt
    P11166
    Pathways
    Sensory Perception of Sound, Dicarboxylic Acid Transport, L'effet Warburg
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