SLC2A2 anticorps (C-Term)

N° du produit ABIN3043928

Détail du produit anti-SLC2A2 anticorps

Antigène: SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))

Épitope: AA 486-514, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC2A2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 2(SLC2A2) detection. Tested with WB, IHC-P in Human.

Séquence: ETKGKSFEEI AAEFQKKSGS AHRPKAAVE

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 2(SLC2A2) detection. Tested with WB, IHC-P in Human.
Gene Name: solute carrier family 2 (facilitated glucose transporter), member 2
Protein Name: Solute carrier family 2, facilitated glucose transporter member 2

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human SLC2A2 (486-514aa ETKGKSFEEIAAEFQKKSGSAHRPKAAVE), different from the related mouse sequence by five amino acids, and from the related rat sequence by seven amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SLC2A2 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-SLC2A2 (ABIN3043928)

Wu, Guo, Lu, Wu, Pan, Su: "Impact of perinatal exposure to acetaminophen on hepatocellular metabolic function in offspring." dans: American journal of translational research, Vol. 8, Issue 12, pp. 5646-5652, (2017) (PubMed).

Détails sur SLC2A2

Antigène: SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))

Autre désignation: SLC2A2 (SLC2A2 Produits)

Synonymes: anticorps glut2, anticorps wu:fb62h10, anticorps slc2a2, anticorps MGC83262, anticorps SLC2A2, anticorps GLUT2, anticorps GTT2, anticorps Glut2, anticorps AI266973, anticorps Glut-2, anticorps solute carrier family 2 (facilitated glucose transporter), member 2, anticorps solute carrier family 2 member 2 L homeolog, anticorps solute carrier family 2 member 2, anticorps solute carrier family 2, facilitated glucose transporter member 2, anticorps slc2a2, anticorps slc2a2.L, anticorps SLC2A2, anticorps LOC100534484, anticorps Slc2a2

Sujet: SLC2A2, also known as Glucose transporter 2 (GLUT2), is a transmembrane carrier protein that enables protein facilitatedglucose movement across cell membranes. This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene.

Synonyms: liver antibody|Glucose Transporter 2 antibody|Glucose Transporter GLUT2 antibody|Glucose transporter type 2 antibody|Glucose transporter type 2 liver antibody|Glucose transporter, liver/islet antibody|GLUT-2 antibody|GLUT2 antibody|GTR2_HUMAN antibody|GTT2 antibody| SLC2A2 antibody|Solute carrier family 2 (facilitated glucose transporter) member 2 antibody|Solute carrier family 2 facilitated glucose transporter member 2 antibody|Solute carrier family 2, facilitated glucose transporter member 2 antibody

ID gène: 6514

UniProt: P11168

Pathways: L'effet Warburg