SLC6A4 anticorps (N-Term)

N° du produit ABIN3043931

Détail du produit anti-SLC6A4 anticorps

Antigène: SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

Épitope: AA 57-85, N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC6A4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Sodium-dependent serotonin transporter(SLC6A4) detection. Tested with WB, IHC-P in Human,Rat.

Séquence: DDTRHSIPAT TTTLVAELHQ GERETWGKK

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Sodium-dependent serotonin transporter(SLC6A4) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Protein Name: Sodium-dependent serotonin transporter

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human SLC6A4 (57-85aa DDTRHSIPATTTTLVAELHQGERETWGKK), different from the related mouse and rat sequences by six amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SLC6A4 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur SLC6A4

Antigène: SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

Autre désignation: SLC6A4 (SLC6A4 Produits)

Synonymes: anticorps 5-HTT, anticorps 5-HTTLPR, anticorps 5HTT, anticorps HTT, anticorps OCD1, anticorps SERT, anticorps SERT1, anticorps hSERT, anticorps AI323329, anticorps Htt, anticorps Sert, anticorps CG4545, anticorps DmSERT, anticorps DmSerT, anticorps Dmel\\CG4545, anticorps dSERT, anticorps dSERT1, anticorps dSerT, anticorps dSert, anticorps dsert, anticorps SLC6A4, anticorps solute carrier family 6 member 4, anticorps solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, anticorps Serotonin transporter, anticorps huntingtin, anticorps solute carrier family 6 (neurotransmitter transporter), member 4b, anticorps solute carrier family 6 (neurotransmitter transporter), member 4a, anticorps SLC6A4, anticorps Slc6a4, anticorps SerT, anticorps LOC100540532, anticorps slc6a4, anticorps slc6a4b, anticorps slc6a4a

Sujet: SLC6A4 (Solute carrier family 6, member 4), also known as SERT (serotonin transporter), is a monoamine transporter protein. The SLC6A4 gene spans 31 kb and contains 14 exons. This protein integral membrane protein transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. This transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is the target of many antidepressant medications, including those of the SSRI class. It is a member of the sodium: neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, post-traumatic stress disorder and depression-susceptibility in people experiencing emotional trauma.

Synonyms: 5 HTT antibody|5 HTTLPR antibody|5 hydroxytryptamine (serotonin) transporter antibody|5 hydroxytryptamine transporter antibody|5HT transporter antibody|5HTT antibody|hSERT antibody|HTT antibody|Na+/Cl- dependent serotonin transporter antibody|OCD1 antibody| SC6A4_HUMAN antibody|Serotonin transporter 1 antibody|SERT antibody|SERT1 antibody|SLC6A4 antibody|Sodium dependent serotonin transporter antibody|Sodium-dependent serotonin transporter antibody|Solute carrier family 6 (neurotransmitter transporter) member 4 antibody|solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 antibody|Solute carrier family 6 member 4 antibody

ID gène: 6532

UniProt: P31645