SLC9A1 anticorps (AA 543-815)
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- Antigène Voir toutes SLC9A1 Anticorps
- SLC9A1 (Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1))
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Épitope
- AA 543-815
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SLC9A1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Rabbit IgG polyclonal antibody for Sodium/hydrogen exchanger 1(SLC9A1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Sodium/hydrogen exchanger 1(SLC9A1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
Protein Name: Sodium/hydrogen exchanger 1 - Purification
- Immunogen affinity purified.
- Immunogène
- E.coli-derived human SLC9A1 recombinant protein (Position: H543-Q815). Human SLC9A1 shares 92% and 93% amino acid (aa) sequences identity with mouse and rat SLC9A1, respectively.
- Isotype
- IgG
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for SLC9A1 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Antigène
- SLC9A1 (Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1))
- Autre désignation
- SLC9A1 (SLC9A1 Produits)
- Synonymes
- anticorps AT-NHX1, anticorps ATNHX, anticorps ATNHX1, anticorps NA(+)/H(+) ANTIPORTER, anticorps Na+/H+ exchanger 1, anticorps T21B4.60, anticorps T21B4_60, anticorps AW554487, anticorps Apnh, anticorps Nhe1, anticorps swe, anticorps NHE-1, anticorps NHE1, anticorps APNH, anticorps Na+/H+ exchanger 1, anticorps solute carrier family 9 (sodium/hydrogen exchanger), member 1, anticorps solute carrier family 9 member A1, anticorps NHX1, anticorps Slc9a1, anticorps SLC9A1
- Sujet
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NHE1, also known as SLC9A1, is an isoform of sodium-hydrogen antiporter that in humans is encoded by the SLC9A1 gene. It is mapped to 1p36.11. NHE1 is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells. It is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, tumor promoters, and others. The plasma membrane ion exchanger NHE1 acts as an anchor for actin filaments to control the integrity of the cortical cytoskeleton. And a structural role for NHE1 in regulating the cortical cytoskeleton that is independent of its function as an ion exchanger. NHE1 is a plausible candidate gene for human essential hypertension.
Synonyms: amiloride-sensitive antibody|APNH antibody|APNH1 antibody|FLJ42224 antibody|Na Li countertransporter antibody|Na(+)/H(+) antiporter antibody|Na(+)/H(+) exchanger 1 antibody|Na+ H+ antiporter amiloride-sensitive antibody|Na+ H+ antiporter antibody|Na+ H+ exchanger 1 antibody|NHE-1 antibody|NHE1 antibody|OTTHUMP00000004468 antibody|SL9A1_HUMAN antibody|SLC9A1 antibody|Sodium hydrogen exchanger 1 antibody|Sodium/hydrogen exchanger 1 antibody|solute carrier family 9 antibody|Solute carrier family 9 member 1 antibody|Solute carrier family 9 sodium hydrogen exchanger isoform 1 antiporter Na+ H+ amiloride sensitive antibody|Solute carrier family 9 subfamily A (NHE1 cation proton antiporter 1) member 1 antibody|Solute carrier family 9 subfamily A member 1 antibody - ID gène
- 6548
- UniProt
- P19634
- Pathways
- Glycosaminoglycan Metabolic Process, Proton Transport
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