Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

BAG3 anticorps (C-Term)

BAG3 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3043976
  • Antigène Voir toutes BAG3 Anticorps
    BAG3 (BCL2-Associated Athanogene 3 (BAG3))
    Épitope
    • 15
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 491-506, C-Term
    Reactivité
    • 59
    • 24
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 60
    • 3
    • 1
    Lapin
    Clonalité
    • 52
    • 12
    Polyclonal
    Conjugué
    • 29
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BAG3 est non-conjugé
    Application
    • 40
    • 22
    • 13
    • 13
    • 13
    • 9
    • 7
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 3(BAG3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Séquence
    LEKLEQKAID VPGQVQ
    Réactivité croisée (Details)
    Predicted Cross Reactivity: mouse, rat
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Attributs du produit
    Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 3(BAG3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: BCL2-associated athanogene 3
    Protein Name: BAG family molecular chaperone regulator 3
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence at the C-terminus of human Bag3(491-506aa LEKLEQKAIDVPGQVQ), identical to the related mouse and rat sequences.
    Isotype
    IgG
    Top Product
    Discover our top product BAG3 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, The detection limit for BAG3 is approximately 0.5 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Thimerosal (Merthiolate), Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Date de péremption
    12 months
  • Antigène
    BAG3 (BCL2-Associated Athanogene 3 (BAG3))
    Autre désignation
    BAG3 (BAG3 Produits)
    Synonymes
    anticorps bag3-A, anticorps MGC53113, anticorps zgc:100859, anticorps BAG3, anticorps ATBAG3, anticorps BCL-2-associated athanogene 3, anticorps T28J14.160, anticorps T28J14_160, anticorps BAG-3, anticorps BIS, anticorps CAIR-1, anticorps MFM6, anticorps AA407278, anticorps Bis, anticorps mg638, anticorps BCL2 associated athanogene 3 L homeolog, anticorps BCL2-associated athanogene 3, anticorps BCL2 associated athanogene 3, anticorps BCL-2-associated athanogene 3, anticorps Bcl2-associated athanogene 3, anticorps bag3.L, anticorps bag3, anticorps BAG3, anticorps Bag3
    Sujet
    BAG family molecular chaperone regulator 3(BAG3) is a member of a conserved family of cyto-protective proteins that bind to and regulate Hsp70 family molecular chaperones. BAG3 mutations are responsible for familial dilated cardiomyopathy. BAG3 polymorphisms are also associated with sporadic forms of the disease together with HSPB7 locus. In muscle cells, BAG3 cooperates with the molecular chaperones Hsc70 and HspB8 to induce the degradation of mechanically damaged cytoskeleton components in lysosomes. This process is called chaperone-assisted selective autophagy(CASA) and is essential for maintaining muscle activity in flies, mice and men.

    Synonyms: BAG 3 antibody|BAG family molecular chaperone regulator 3 antibody|BAG-3 antibody|Bag3 antibody|BAG3_HUMAN antibody|Bcl 2 binding protein antibody|Bcl-2-associated athanogene 3 antibody|Bcl-2-binding protein Bis antibody|BCL2 associated athanogene 3 antibody|BCL2 binding athanogene 3 antibody|BIS antibody|Docking protein CAIR 1 antibody|Docking protein CAIR-1 antibody
    UniProt
    O95817
Vous êtes ici:
Support technique