TJP2 anticorps (C-Term)

N° du produit ABIN3044036

Détail du produit anti-TJP2 anticorps

Antigène: TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))

Épitope: AA 1149-1167, C-Term

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TJP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Tight junction protein ZO-2(TJP2) detection. Tested with WB, IHC-P in Mouse,Rat.

Séquence: AHSKRGYYSQ PSRYRDTEL

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Tight junction protein ZO-2(TJP2) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: tight junction protein 2
Protein Name: Tight junction protein ZO-2

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of mouse TJP2(1149-1167aa AHSKRGYYSQPSRYRDTEL), identical to the related rat sequence.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, The detection limit for TJP2 is approximately 2.5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TJP2

Antigène: TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))

Autre désignation: TJP2 (TJP2 Produits)

Synonymes: anticorps C9DUPq21.11, anticorps DFNA51, anticorps DUP9q21.11, anticorps X104, anticorps ZO2, anticorps ZO-2, anticorps zo2, anticorps tjp2, anticorps x104, anticorps zo-2, anticorps wu:fb62b09, anticorps zgc:92094, anticorps tight junction protein 2, anticorps tight junction protein 2 L homeolog, anticorps tight junction protein 2b (zona occludens 2), anticorps TJP2, anticorps Tjp2, anticorps tjp2.L, anticorps tjp2b

Sujet: TJP2(Tight Junction Protein 2), also known as Zona Occludens 2 or ZO2, is a protein that in humans is encoded by the TJP2 gene. Tight junction proteins(TJPs) belong to a family of membrane-associated guanylate kinase(MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. Duclos et al.(1994) mapped the TJP2 gene telomeric to the Friedreich ataxia critical region on chromosome 9q13-q21. TJP2 lies about 70 kb centromeric to the X123 gene and is transcribed in the centromere-to-telomere direction. Using in vitro assays and immunoprecipitation studies, Itoh et al.(1999) showed that the mouse Tjp1, Tjp2, and Tjp3 PDZ1 domains interacted with the C-terminal cytoplasmic domains of Cldn1 through Cldn8. In the mouse inner ear, Walsh et al.(2010) found that Tjp2 expression decreased rapidly between E16.5 and age 1 week to a level in adult mice that was approximately 50 % of the level at birth(P0).

Synonyms: Friedreich ataxia region gene X104(tight junction protein ZO-2) antibody|MGC26306 antibody|Tight junction protein 2 antibody|Tight junction protein ZO 2 antibody|Tight junction protein ZO-2 antibody|TJP2 antibody|X104 antibody|ZO 2 antibody|ZO-2 antibody|ZO2 antibody|ZO2_HUMAN antibody|Zona occludens protein 2 antibody|Zonula occludens protein 2 antibody

UniProt: Q9Z0U1