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ALDH2 anticorps (N-Term)

ALDH2 Reactivité: Humain, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3044072
  • Antigène Voir toutes ALDH2 Anticorps
    ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))
    Épitope
    • 10
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 18-33, N-Term
    Reactivité
    • 80
    • 21
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat
    Hôte
    • 61
    • 17
    • 2
    Lapin
    Clonalité
    • 59
    • 21
    Polyclonal
    Conjugué
    • 39
    • 10
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp ALDH2 est non-conjugé
    Application
    • 66
    • 43
    • 40
    • 17
    • 13
    • 13
    • 9
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit IgG polyclonal antibody for Aldehyde dehydrogenase, mitochondrial(ALDH2) detection. Tested with WB, IHC-P in Human,Rat.
    Séquence
    SAAATQAVPA PNQQPE
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Aldehyde dehydrogenase, mitochondrial(ALDH2) detection. Tested with WB, IHC-P in Human,Rat.
    Gene Name: aldehyde dehydrogenase 2 family(mitochondrial)
    Protein Name: Aldehyde dehydrogenase, mitochondrial
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence at the N-terminus of human ALDH2(18-33aa SAAATQAVPAPNQQPE), different from the related mouse sequence by two amino acids, and from the related rat sequence by one amino acid.
    Isotype
    IgG
    Top Product
    Discover our top product ALDH2 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Thimerosal (Merthiolate), Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Date de péremption
    12 months
  • Antigène
    ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))
    Autre désignation
    ALDH2 (ALDH2 Produits)
    Synonymes
    anticorps aldh2, anticorps aldh2a, anticorps zgc:63786, anticorps MGC80785, anticorps aldh-e2, anticorps aldhi, anticorps aldm, anticorps rf2b, anticorps ALDH-E2, anticorps ALDHI, anticorps ALDM, anticorps Ahd-5, anticorps Ahd5, anticorps aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1, anticorps aldehyde dehydrogenase 2 family (mitochondrial) L homeolog, anticorps aldehyde dehydrogenase 2 family (mitochondrial), anticorps aldehyde dehydrogenase 2, anticorps aldehyde dehydrogenase, anticorps aldehyde dehydrogenase (NAD(+)), anticorps hypothetical protein, anticorps aldehyde dehydrogenase 2, mitochondrial, anticorps aldh2.1, anticorps aldh2.L, anticorps aldh2, anticorps ALDH2, anticorps RHA1_RS43090, anticorps aldH2, anticorps OE_RS03015, anticorps Aldh2
    Sujet
    ALDH2(Aldehyde Dehydrogenase 2 Family) is a human gene. The enzyme encoded by this gene belongs to the aldehyde dehydrogenase family of enzymes that catalyze the chemical transformation from acetaldehyde to acetic acid. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Hsu et al.(1985) assigned the ALDH2 locus to chromosome 12 by means of a cDNA probe and Southern blot analysis of somatic cell hybrids. Using an unbiased proteomic search, Chen et al.(2008) identified mitochondrial ALDH2 as an enzyme whose activation correlated with reduced ischemic heart damage in rodent models. A high-throughput screen identified a small molecule activator of ALDH2, which they called Alda-1, that, when administered to rats before an ischemic event, reduced infarct size by 60 % , most likely through its inhibitory effect on the formation of cytotoxic aldehydes.

    Synonyms: Acetaldehyde dehydrogenase 2 antibody|Aldehyde dehydrogenase 2 family(mitochondrial) antibody|Aldehyde dehydrogenase 2 family antibody|Aldehyde dehydrogenase mitochondrial antibody|Aldehyde dehydrogenase, mitochondrial antibody|ALDH 2 antibody|ALDH class 2 antibody|ALDH E2 antibody|ALDH-E2 antibody|Aldh2 antibody|ALDH2_HUMAN antibody|ALDHI antibody|ALDM antibody|Liver mitochondrial ALDH antibody|MGC1806 antibody|Mitochondrial aldehyde dehydrogenase 2 antibody|MS767 antibody|Nucleus encoded mitochondrial aldehyde dehydrogenase 2 antibody
    UniProt
    P05091
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