SDHB anticorps (N-Term)

N° du produit ABIN3044278

Détail du produit anti-SDHB anticorps

Antigène: SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Épitope: N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SDHB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Succinate dehydrogenase[ubiquinone] iron-sulfur subunit, mitochondrial(SDHB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: FAIYRWDPDK AGDKPHMQ

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Succinate dehydrogenase[ubiquinone] iron-sulfur subunit, mitochondrial(SDHB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: succinate dehydrogenase complex, subunit B, iron sulfur(Ip)
Protein Name: Succinate dehydrogenase[ubiquinone] iron-sulfur subunit, mitochondrial

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human SDHB(42-59 FAIYRWDPDKAGDKPHMQ), different from the related rat sequence by one amino acid and mouse sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SDHB

Antigène: SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Autre désignation: SDHB (SDHB Produits)

Synonymes: anticorps succinate dehydrogenase 2-3, anticorps CG3283, anticorps Dmel\\CG3283, anticorps Ip, anticorps SDH, anticorps SDH-IP, anticorps SDH-Ip, anticorps SDHb, anticorps sdhB, anticorps CWS2, anticorps IP, anticorps PGL4, anticorps SDH1, anticorps SDH2, anticorps SDHIP, anticorps 0710008N11Rik, anticorps fj46d06, anticorps wu:fj46d06, anticorps succinate dehydrogenase complex iron sulfur subunit B, anticorps succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3, anticorps Succinate dehydrogenase, subunit B (iron-sulfur), anticorps succinate dehydrogenase complex subunit B, iron sulfur (Ip), anticorps succinate dehydrogenase complex, subunit B, iron sulfur (Ip), anticorps succinate dehydrogenase complex subunit B, iron sulfur (Ip) S homeolog, anticorps SDHB, anticorps SDH2-3, anticorps SdhB, anticorps sdhb, anticorps Sdhb, anticorps sdhb.S

Sujet: SDHB(Succinate Dehydrogenase Complex, Subunit B, iron sulfur protein), also known as iron-sulfur subunit of complex II(Ip) or SDH2, HOMOLOG OF, is a protein that in humans is encoded by the SDHB gene. SDHB is one of four protein subunits forming succinate dehydrogenase, the other three being SDHA, SDHC and SDHD. The SDHB subunit is connected to the SDHA subunit on the hydrophilic, catalytic end of the SDH complex. The SDHB gene is mapped on 1p36.13. The entire SDHB transcript is encoded by 8 exons within approximately 40 kb by Au et al(1995). Pollard et al.(2005) stated that the nuclear-encoded Krebs cycle enzymes fumarate hydratase and succinate dehydrogenases like SDHB act as tumor suppressors, and germline mutations in these genes predispose individuals to leiomyomas and renal cancer and to paragangliomas, respectively. In affected members of families with paragangliomas-4, mutations were identified in the SDHB gene.

Synonyms: CWS2 antibody|DHSB_HUMAN antibody|FLJ92337 antibody|IP antibody|Iron sulfur subunit antibody|Iron sulfur subunit of complex II antibody|Iron-sulfur subunit of complex II antibody|mitochondrial antibody|OTTHUMP00000044624 antibody|PGL 4 antibody|PGL4 antibody|SDH 1 antibody|SDH antibody|SDH1 antibody|SDH2 antibody|SDHB antibody|SDHIP antibody|Succinate dehydrogenase[ubiquinone] iron sulfur protein mitochondrial antibody|Succinate dehydrogenase[ubiquinone] iron-sulfur subunit antibody|succinate dehydrogenase[ubiquinone] iron-sulfur subunit, mitochondrial antibody|Succinate Dehydrogenase 1 Iron Sulfur Subunit antibody|Succinate dehydrogenase complex subunit B iron sulfur antibody|Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein antibody|succinate dehydrogenase complex, subunit B, iron sulfur(Ip) antibody|Succinate dehydrogenase iron sulfur protein antibody

UniProt: P21912