AIMP2 anticorps (Middle Region)

N° du produit ABIN3044411

Détail du produit anti-AIMP2 anticorps

Antigène: AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))

Épitope: AA 298-320, Middle Region

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AIMP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Aminoacyl tRNA synthase complex-interacting multifunctional protein 2(AIMP2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: NVQRWMRSCE NLAPFNTALK LLK

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Aminoacyl tRNA synthase complex-interacting multifunctional protein 2(AIMP2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Protein Name: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human AIMP2/p38(298-320aa NVQRWMRSCENLAPFNTALKLLK), different from the related rat and mouse sequences by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-AIMP2 (ABIN3044411)

Sun, Yang, Wang, Sun, Dong: "Crocin attenuates cisplatin-induced liver injury in the mice." dans: Human & experimental toxicology, Vol. 33, Issue 8, pp. 855-62, (2015) (PubMed).

Zheng, Liu, Liu, Ma, Zhou, Chen, Chang, Wang, Yang, He: "Cucurbitacin B inhibits growth and induces apoptosis through the JAK2/STAT3 and MAPK pathways in SH?SY5Y human neuroblastoma cells." dans: Molecular medicine reports, Vol. 10, Issue 1, pp. 89-94, (2014) (PubMed).

Zhao, Li: "Altholactone induces reactive oxygen species-mediated apoptosis in bladder cancer T24 cells through mitochondrial dysfunction, MAPK-p38 activation and Akt suppression." dans: Oncology reports, Vol. 31, Issue 6, pp. 2769-75, (2014) (PubMed).

Détails sur AIMP2

Antigène: AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))

Autre désignation: AIMP2 (AIMP2 Produits)

Synonymes: anticorps jtv1, anticorps MGC53242, anticorps pro0992, anticorps JTV1, anticorps JTV-1, anticorps P38, anticorps AA407136, anticorps AA407225, anticorps Aimp2(p38), anticorps Jtv1, anticorps aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 L homeolog, anticorps aminoacyl tRNA synthetase complex-interacting multifunctional protein 2, anticorps aminoacyl tRNA synthetase complex interacting multifunctional protein 2, anticorps aimp2.L, anticorps aimp2, anticorps AIMP2, anticorps Aimp2

Sujet: AIMP2, Aminoacyl tRNA synthetase complex-interacting multifunctional protein 2, also known as AIMP2, is an enzyme that in humans is encoded by the AIMP2 gene. AIMP2 encodes a predicted 312-amino acid protein. The AIMP2 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. AIMP2 and HRI overlap slightly and are arranged in a tail-to-tail fashion. AIMP2 and PMS2 are separated by approximately 200 base pairs and are arranged head-to-head. AIMP2 is transcribed in the opposite direction compared to HRI and PMS2. AIMP2 is a scaffold required for the assembly and stability of the multi-tRNA synthetase complex. AIMP2 can work as a mediator of TGF-beta signaling and its functional importance in the control of MYC during lung differentiation.

Synonyms: Aimp2 antibody|AIMP2_HUMAN antibody|Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 antibody|Aminoacyl tRNA synthetase complex interacting multifunctional protein 2 antibody|ARS interacting multi functional protein 2 antibody|JTV 1 antibody|JTV 1 protein antibody|JTV1 antibody|Multisynthase complex auxiliary component p38 antibody|Multisynthetase complex auxiliary component p38 antibody|P38 antibody|PRO0992 antibody|Protein JTV 1 antibody|Protein JTV-1 antibody|tRNA SYNTHETASE COFACTOR p38 antibody

UniProt: Q13155