SCN1A anticorps (C-Term)

N° du produit ABIN3044542

Détail du produit anti-SCN1A anticorps

Antigène: SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))

Épitope: AA 1981-2009, C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCN1A est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Sodium channel protein type 1 subunit alpha(SCN1A) detection. Tested with WB in Human,Mouse,Rat.

Séquence: ACPPSYDRVT KPIVEKHEQE GKDEKAKGK

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Sodium channel protein type 1 subunit alpha(SCN1A) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: sodium voltage-gated channel alpha subunit 1
Protein Name: Sodium channel protein type 1 subunit alpha

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Scn1a (1981-2009aa ACPPSYDRVTKPIVEKHEQEGKDEKAKGK), identical to the related rat sequence.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur SCN1A

Antigène: SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))

Autre désignation: SCN1A (SCN1A Produits)

Synonymes: anticorps SCN9A, anticorps SCN1A, anticorps B230332M13, anticorps Nav1.1, anticorps EIEE6, anticorps FEB3, anticorps FEB3A, anticorps FHM3, anticorps GEFSP2, anticorps HBSCI, anticorps NAC1, anticorps SCN1, anticorps SMEI, anticorps sodium voltage-gated channel alpha subunit 1, anticorps sodium voltage-gated channel alpha subunit 9, anticorps sodium channel, voltage-gated, type I, alpha, anticorps SCN1A, anticorps SCN9A, anticorps Scn1a

Sujet: Nav1.1, also known as the sodium channel, voltage-gated, type I, alpha subunit (SCN1A), is a protein which in humans is encoded by the SCN1A gene. Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons. Each sodium channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits. This gene encodes a sodium channel alpha subunit, which has four homologous domains, each of which contains six transmembrane regions. Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript.

Synonyms: brain sodium channel type I antibody|EIEE6 antibody|FEB3 antibody|FEB3A antibody|FHM3 antibody|GEFS+2 antibody|GEFSP2 antibody|HBSC I antibody|HBSCI antibody|NAC1 antibody|Nav 1.1 antibody|RBI antibody|SCN1 antibody|Scn1a antibody|SCN1A_HUMAN antibody|SMEI antibody| Sodium channel protein brain I alpha subunit antibody|Sodium channel protein brain I subunit alpha antibody|Sodium channel protein type 1 subunit alpha antibody|Sodium channel protein type I subunit alpha antibody|Sodium channel voltage gated type 1 alpha subunit antibody|Sodium channel voltage gated type I alpha polypeptide antibody|Voltage-gated sodium channel subunit alpha Nav1.1 antibody

ID gène: 6323

UniProt: P35498