CACNA1I anticorps

N° du produit ABIN306882

Détail du produit anti-CACNA1I anticorps

Antigène: CACNA1I (Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CACNA1I est non-conjugé

Application: Western Blotting (WB)

Isotype: IgG

Information d'application

Indications d'application: This antibody can be used for Western blotting (5-10 ug/ml). Positive Control: Rat brain lysate.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/ml

Stock: -20 °C

Détails sur CACNA1I

Antigène: CACNA1I (Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I))

Autre désignation: Voltage-dependent T-type calcium channel subunit alpha-1I (CACNA1I Produits)

Synonymes: anticorps CACNA1L, anticorps Ca(V)3.3, anticorps Cav3.3, anticorps ca(v)3.3, anticorps si:ch211-51h13.1, anticorps Ca(v)3.3, anticorps calcium voltage-gated channel subunit alpha1 I, anticorps voltage-dependent T-type calcium channel subunit alpha-1I, anticorps calcium channel, voltage-dependent, alpha 1I subunit, anticorps calcium channel, voltage-dependent, T type, alpha 1I subunit, anticorps CACNA1I, anticorps LOC100555412, anticorps Cacna1i, anticorps cacna1i

Sujet: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. Using co-transfection techniques we investigated the functional effects of each of the gamma subunits on the biophysics of the T-type VSCC encoded by the alpha(1I) subunit. This revealed a substantially slowed rate of deactivation in the presence of gamma(2). In contrast, there was no significant corresponding effect of either gamma(3) or gamma(4) on alpha(1I) subunit-mediated currents.(2)Synonyms: Voltage-gated calcium channel subunit alpha Cav3.3,.

UniProt: Q9P0X4