Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (C-Term) anticorps

Détails pour le produit réf. ABIN314245
Antigène
  • FSGS2
  • TRP6
  • AV025995
  • LLHWJM002
  • LLHWJM003
  • LLHWJM004
  • TRP-6
  • Trrp6
  • mtrp6
  • trp6
  • bZ1P14.9
  • si:rp71-1p14.9
  • trpc6
  • transient receptor potential cation channel subfamily C member 6
  • transient receptor potential cation channel, subfamily C, member 6
  • transient receptor potential cation channel, subfamily C, member 6a
  • TRPC6
  • Trpc6
  • trpc6a
  • trpc6
Épitope
C-Term
38
20
6
3
2
2
2
1
1
1
1
1
1
1
Reactivité
Humain, Souris
100
59
34
7
5
4
4
3
2
2
2
1
Hôte
Chèvre
78
42
6
1
1
Clonalité
Polyclonal
Conjugué
Inconjugué
4
4
4
4
4
4
Application
Immunoprecipitation (IP), ELISA, Western Blotting (WB)
105
60
37
13
12
5
3
2
2
2
1
Options
Immunogène Peptide with sequence C-EKLSMEPNQEETNR corresponding to C-Terminus according to NP_004612.2.
Purification Immunogen affinity purified
Antigène
Autre désignation TRPC6 (TRPC6 Antibody Extrait)
Sujet Gene Symbol: TRPC6
Poids moléculaire Theoretical MW: 106 kDa
ID gène 7225
UniProt Q9Y210
Indications d'application Western Blot 0.03 - 0.1 μg/mL, Immunoprecipitation 1:10 - 1:500, Peptide ELISA Detection limit 1:128000WB: Approx. 110 kDa band observed in human placenta lysates (calculated MW of 106Da according to NP_004612.2). IP usage is reported in scientific literature (PMID: 23948707). The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Commentaires

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer 0.5 mg/mL Tris ( pH 7.3) and 0.5 % BSA
Buffer contains: 0.02 % Sodium Azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid freeze-thaw cycles
Stock -20 °C
Stockage commentaire Store at -20°C. Avoid freeze-thaw cycles.
Images (Fournisseur)
Western Blotting (WB) image for anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (C-Term) antibody (ABIN314245) Western Blot: TRPC6 Antibody [NBP1-00142] - Analysis of TRPC6 in human placenta lysat...
Produit citée dans: Álvarez-Miguel, Cidad, Pérez-García, López-López: "Differences in TRPC3 and TRPC6 channels assembly in mesenteric vascular smooth muscle cells in essential hypertension." dans: The Journal of physiology, 2016 (PubMed). Méthode utilisée: Western Blotting (WB)

Anderson, Kim, Hagmann, Benzing, Dryer: "Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol." dans: American journal of physiology. Cell physiology, Vol. 305, Issue 3, pp. C276-89, 2013 (PubMed). (Échantillon (espèces): Mouse (Murine)). Détails: Western Blotting

Kim, Anderson, Wilson, Hagmann, Benzing, Dryer: "NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex." dans: American journal of physiology. Cell physiology, Vol. 305, Issue 9, pp. C960-71, 2013 (PubMed). (Échantillon (espèces): Mouse (Murine)). Détails: Immunoprecipitation

Foller, Kasinathan, Koka, Lang, Shumilina, Birnbaumer, Lang, Huber: "TRPC6 contributes to the Ca(2+) leak of human erythrocytes." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 21, Issue 1-3, pp. 183-92, 2008 (PubMed).

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